Benzoyl chloride, 2-chloro-4-[(5-fluoro-2-methylbenzoyl)amino]-

Base Information

• Chemical Name: Benzoyl chloride, 2-chloro-4-[(5-fluoro-2-methylbenzoyl)amino]-
• CAS No.: 168080-80-6
• Molecular Formula: C₁₅H₁₀Cl₂FNO₂
• Molecular Weight: 326.154
• European Community (EC) Number: 605-502-9
• DSSTox Substance ID: DTXSID801185558

Synonyms:168080-80-6;Benzoyl chloride, 2-chloro-4-[(5-fluoro-2-methylbenzoyl)amino]-;SCHEMBL7336714;RZPOBZFSSJQQPZ-UHFFFAOYSA-N;DTXSID801185558;2-Chloro-4-(2-methyl-5-fluorobenzoylamino)benzoyl chloride;2-chloro-4-[(5-fluoro-2-methylbenzoyl)amino]benzoyl chloride;4-[(2-methyl-5-fluorobenzoyl)amino]-2-chlorobenzoyl chloride;4-[(5-fluoro-2-methylbenzoyl)amino]-2-chlorobenzoyl chloride;2-CHLORO-4-(5-FLUORO-2-METHYLBENZAMIDO)BENZOYL CHLORIDE

Chemical Property of Benzoyl chloride, 2-chloro-4-[(5-fluoro-2-methylbenzoyl)amino]-

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 380.3±42.0 °C(Predicted)
• PKA: 11.70±0.70(Predicted)
• Density: 1.435±0.06 g/cm3(Predicted)
• XLogP3: 4.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 325.0072621
• Heavy Atom Count: 21
• Complexity: 407

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=C(C=C(C=C1)F)C(=O)NC2=CC(=C(C=C2)C(=O)Cl)Cl

Technology Process of Benzoyl chloride, 2-chloro-4-[(5-fluoro-2-methylbenzoyl)amino]-

There total 4 articles about Benzoyl chloride, 2-chloro-4-[(5-fluoro-2-methylbenzoyl)amino]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Chloro-4-(5-fluoro-2-methyl-benzoylamino)-benzoic acid (168080-49-7) → 4-[(5-fluoro-2-methylbenzoyl)amino]-2-chlorobenzoyl chloride (168080-80-6)

Guidance literature:

With thionyl chloride;

DOI:10.1021/jm980179c

Reference yield:

methyl 4-amino-2-chlorobenzoate (46004-37-9) → 4-[(5-fluoro-2-methylbenzoyl)amino]-2-chlorobenzoyl chloride (168080-80-6)

Guidance literature:

Multi-step reaction with 3 steps

2: OH^-

3: SOCl₂

With thionyl chloride; hydroxide;

DOI:10.1021/jm980179c

Reference yield:

5-fluoro-2-methylbenzoyl chloride (21900-39-0) → 4-[(5-fluoro-2-methylbenzoyl)amino]-2-chlorobenzoyl chloride (168080-80-6)

Guidance literature:

Multi-step reaction with 3 steps

2: OH^-

3: SOCl₂

With thionyl chloride; hydroxide;

DOI:10.1021/jm980179c

upstream raw materials:

2-Chloro-4-(5-fluoro-2-methyl-benzoylamino)-benzoic acid

methyl 4-amino-2-chlorobenzoate

5-fluoro-2-methylbenzoyl chloride

2-Chloro-4-(5-fluoro-2-methyl-benzoylamino)-benzoic acid methyl ester

Downstream raw materials:

C₂₈H₂₃ClFN₃O₄

C₂₆H₂₁ClFN₃O₂

C₂₃H₁₈ClFN₂O₄

N-[4-[(4,10-dihydro-9H-thieno[2,3-c][1]benzazepin-9-yl)carbonyl]-3-chlorophenyl]-5-fluoro-2-methylbenzamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 168080-80-6 2-chloro-4-{[(5-fluoro-2-methylphenyl)carbonyl]amino}benzoyl chloride

Send

Send

Metric Ton KG G Pound L ML

Send

Send