tert-butyl 2-chloro-4-((2,2,2-trifluoroethylamino)methyl)benzoate

Base Information

• Chemical Name: tert-butyl 2-chloro-4-((2,2,2-trifluoroethylamino)methyl)benzoate
• CAS No.: 1190947-54-6
• Molecular Formula: C₁₄H₁₇ClF₃NO₂
• Molecular Weight: 323.743
• Mol file: 1190947-54-6.mol

Synonyms:tert-butyl 2-chloro-4-((2,2,2-trifluoroethylamino)methyl)benzoate

Chemical Property of tert-butyl 2-chloro-4-((2,2,2-trifluoroethylamino)methyl)benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of tert-butyl 2-chloro-4-((2,2,2-trifluoroethylamino)methyl)benzoate

There total 1 articles about tert-butyl 2-chloro-4-((2,2,2-trifluoroethylamino)methyl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butyl 4-(bromomethyl)-2-chlorobenzoate (879088-82-1) + trifluoroethylamine (753-90-2) → tert-butyl 2-chloro-4-((2,2,2-trifluoroethylamino)methyl)benzoate (1190947-54-6)

Guidance literature:

In dimethyl sulfoxide;

Reference yield:

tert-butyl 2-chloro-4-((2,2,2-trifluoroethylamino)methyl)benzoate (1190947-54-6) → 2-chloro-4-((2,2,2-trifluoroethylamino)methyl)benzoic acid (1190947-55-7)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; at 45 ℃;

upstream raw materials:

tert-butyl 4-(bromomethyl)-2-chlorobenzoate

trifluoroethylamine

Downstream raw materials:

2-chloro-4-((2,2,2-trifluoroethylamino)methyl)benzoic acid