methyl cis-<5-(ethoxycarbonyl)oxy-3-cyclohexene-1-carboxylate>

Base Information

• Chemical Name: methyl cis-<5-(ethoxycarbonyl)oxy-3-cyclohexene-1-carboxylate>
• CAS No.: 144681-41-4
• Molecular Formula: C₁₁H₁₆O₅
• Molecular Weight: 228.245
• Mol file: 144681-41-4.mol

Synonyms:methyl cis-<5-(ethoxycarbonyl)oxy-3-cyclohexene-1-carboxylate>

Chemical Property of methyl cis-<5-(ethoxycarbonyl)oxy-3-cyclohexene-1-carboxylate>

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl cis-<5-(ethoxycarbonyl)oxy-3-cyclohexene-1-carboxylate>

There total 1 articles about methyl cis-<5-(ethoxycarbonyl)oxy-3-cyclohexene-1-carboxylate> which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

chloroformic acid ethyl ester (541-41-3) + cis-methyl 5-hydroxycyclohex-3-enecarboxylate (54911-89-6,68295-79-4,68295-80-7,74561-99-2,79433-96-8,121053-59-6,121053-60-9,126640-65-1) → methyl cis-<5-(ethoxycarbonyl)oxy-3-cyclohexene-1-carboxylate> (144681-41-4)

Guidance literature:

With dmap; triethylamine; In diethyl ether; for 24h;

DOI:10.1016/S0040-4020(01)81764-6

Reference yield: 71.0%

2-Sulfanylpyridine (2637-34-5,73018-10-7) + methyl cis-<5-(ethoxycarbonyl)oxy-3-cyclohexene-1-carboxylate> (144681-41-4) → cis-3-(pyridyl-2-thio)-5-carbomethoxy-1-cyclohexene

Guidance literature:

With tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; 1,4-di(diphenylphosphino)-butane; In tetrahydrofuran; at 50 ℃; for 24h;

DOI:10.1016/S0040-4020(01)81764-6

Reference yield:

methyl cis-<5-(ethoxycarbonyl)oxy-3-cyclohexene-1-carboxylate> (144681-41-4) → (1S,5S)-5-Furan-2-yl-cyclohex-3-enecarboxylic acid methyl ester

Guidance literature:

Multi-step reaction with 2 steps

2: NaH / methanol

With sodium hydride; In methanol;

DOI:10.1021/jo960458c

upstream raw materials:

chloroformic acid ethyl ester

cis-methyl 5-hydroxycyclohex-3-enecarboxylate

Downstream raw materials:

2-((1S,5S)-5-Methoxycarbonyl-cyclohex-2-enyl)-malonic acid diethyl ester

2-((1S,5R)-5-Methoxycarbonyl-cyclohex-2-enyl)-malonic acid diethyl ester

methyl trans-5-phenyl-3-cyclohexene-1-carboxylate