Hydralazine acetone hydrazone

Base Information

• Chemical Name: Hydralazine acetone hydrazone
• CAS No.: 56173-18-3
• Molecular Formula: C₁₁H₁₂N₄
• Molecular Weight: 200.243
• DSSTox Substance ID: DTXSID60204704
• Nikkaji Number: J86.361K
• Mol file: 56173-18-3.mol

Synonyms:hydralazine acetone hydrazone;hydralazine acetonide

Chemical Property of Hydralazine acetone hydrazone

Chemical Property:

• Vapor Pressure: 4.08E-07mmHg at 25°C
• Melting Point: 99-102°C
• Refractive Index: 1.4260 (estimate)
• Boiling Point: 415.6°C at 760 mmHg
• Flash Point: 205.1°C
• PSA: 50.17000
• Density: 1.17g/cm³
• LogP: 2.51050
• Storage Temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• Solubility.: Chloroform, Dichloromethane, Ethyl Acetate, Methanol
• XLogP3: 1.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 200.106196400
• Heavy Atom Count: 15
• Complexity: 235

Purity/Quality:

98%Min ^*data from raw suppliers

Acetone hydralazine hydrazone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=NNC1=NN=CC2=CC=CC=C21)C
• Uses: A Hydralazine (HP) (H716531) metabolite A major metabolite of Hydralazine (H716531).

Technology Process of Hydralazine acetone hydrazone

There total 2 articles about Hydralazine acetone hydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

hydralazine hydrochloride (304-20-1) + acetone (67-64-1) → acetone phthalazine-1-ylhydrazone (56173-18-3,67458-29-1)

Guidance literature:

In water; for 0.166667h; Ambient temperature;

DOI:10.1021/js950218x

Reference yield:

→ acetone phthalazine-1-ylhydrazone (56173-18-3,67458-29-1)

Guidance literature:

/BRN= 137216/;

DOI:10.1002/hlca.19510340122

Reference yield:

acetone phthalazine-1-ylhydrazone (56173-18-3,67458-29-1) + 2-oxo-propionic acid (127-17-3) → hydralazine pyruvic acid hydrazone (67536-13-4)

Guidance literature:

at 37 ℃; Rate constant; Mechanism; pH 7.4;

DOI:10.1002/jps.2600770320

upstream raw materials:

hydralazine hydrochloride

acetone

Downstream raw materials:

hydralazine pyruvic acid hydrazone

Refernces