2,4,5-tribromoaniline

Base Information

• Chemical Name: 2,4,5-tribromoaniline
• CAS No.: 615-86-1
• Molecular Formula: C₆H₄Br₃N
• Molecular Weight: 329.816
• Mol file: 615-86-1.mol

Synonyms:2,4,5-tribromoaniline

Chemical Property of 2,4,5-tribromoaniline

Chemical Property:

• Melting Point: 80-81 °C
• Boiling Point: 318.0±37.0 °C(Predicted)
• PKA: 0.76±0.10(Predicted)
• Density: 2.351±0.06 g/cm3(Predicted)

Purity/Quality:

97% ^*data from raw suppliers

2,4,5-TRIBROMOANILINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,4,5-tribromoaniline

There total 9 articles about 2,4,5-tribromoaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

2,5-dibromoaniline (3638-73-1) → 2,4,5-tribromoaniline (615-86-1)

Guidance literature:

With bromine; In tetrachloromethane; at -10 - 20 ℃; for 1h;

DOI:10.1002/ejoc.201201188

Reference yield:

(2,4,5-tribromo-phenyl)-carbamic acid ethyl ester + aniline (62-53-3) → N,N-diphenylurea (603-54-3) + 2,4,5-tribromoaniline (615-86-1)

Guidance literature:

Reference yield:

1.4-dibromobenzene (106-37-6) → 2,4,5-tribromoaniline (615-86-1)

Guidance literature:

Multi-step reaction with 3 steps

1: nitric acid; sulfuric acid / dichloromethane / 0.5 h

2: tin(II) chloride dihdyrate / tetrahydrofuran

3: bromine / tetrachloromethane / 1 h / -10 - 20 °C

With tin(II) chloride dihdyrate; sulfuric acid; bromine; nitric acid; In tetrahydrofuran; tetrachloromethane; dichloromethane;

DOI:10.1002/ejoc.201201188

upstream raw materials:

1,2,4-tribromo-5-nitrobenzene

aniline

m-Bromoaniline

4,5,7-tribromo-indoline-2,3-dione

Downstream raw materials:

1,2,4,5-tetrabromobenzene

2,4,5-tribromophenol

1,2,4-tribromo-5-fluoro-benzene

1,2,4-tribromobenzene