Technology Process of C66H78N6O13
There total 3 articles about C66H78N6O13 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
1,3-bis-{(N1'-[3'',4''-bis(benzyloxy)benzoyl]-N4'-acetyl)spermidinyl}-2-isopropyl citrate;
With
lithium hydroxide;
In
tetrahydrofuran; water;
at 0 ℃;
for 0.666667h;
Inert atmosphere;
Darkness;
In
tetrahydrofuran; water;
for 0.166667h;
Inert atmosphere;
DOI:10.1002/ejoc.201301340
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: dicyclohexyl-carbodiimide / acetonitrile / 20 h / 20 °C / Inert atmosphere
2.1: triethylamine / N,N-dimethyl-formamide / 0.25 h / Cooling with ice; Inert atmosphere; Darkness
2.2: 20 °C / Molecular sieve; Cooling with ice; Ionic liquid; Darkness
3.1: lithium hydroxide / water; tetrahydrofuran / 0.67 h / 0 °C / Inert atmosphere; Darkness
3.2: strongly acidic ion exchange resin (Dowex50WX8-100, 50–100 mesh) / 0.17 h / Inert atmosphere
With
triethylamine; dicyclohexyl-carbodiimide; lithium hydroxide;
In
tetrahydrofuran; water; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1002/ejoc.201301340
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: triethylamine / N,N-dimethyl-formamide / 0.25 h / Cooling with ice; Inert atmosphere; Darkness
1.2: 20 °C / Molecular sieve; Cooling with ice; Ionic liquid; Darkness
2.1: lithium hydroxide / water; tetrahydrofuran / 0.67 h / 0 °C / Inert atmosphere; Darkness
2.2: strongly acidic ion exchange resin (Dowex50WX8-100, 50–100 mesh) / 0.17 h / Inert atmosphere
With
triethylamine; lithium hydroxide;
In
tetrahydrofuran; water; N,N-dimethyl-formamide;
DOI:10.1002/ejoc.201301340