Technology Process of C31H25F2N5O5
There total 7 articles about C31H25F2N5O5 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
bis(trichloromethyl) carbonate; C23H23NO3;
With
triethylamine;
In
dichloromethane;
at 0 - 20 ℃;
for 0.25h;
1-(2,6-difluoro-phenyl)-1,4-dihydro-tetrazol-5-one;
With
dmap;
In
toluene;
for 3h;
Reflux;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: potassium carbonate / N,N-dimethyl-formamide / 19 h / 20 °C / Inert atmosphere
2.1: potassium carbonate / N,N-dimethyl-formamide / 24 h
3.1: sulfuric acid; iron / ethanol; water; tetrahydrofuran / 1 h / 0 - 20 °C
4.1: sodium tetrahydroborate; acetic acid / 1 h / 20 °C
5.1: triethylamine / dichloromethane / 0.25 h / 0 - 20 °C
5.2: 3 h / Reflux
With
sodium tetrahydroborate; sulfuric acid; iron; potassium carbonate; acetic acid; triethylamine;
In
tetrahydrofuran; ethanol; dichloromethane; water; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: potassium carbonate / N,N-dimethyl-formamide / 24 h
2.1: sulfuric acid; iron / ethanol; water; tetrahydrofuran / 1 h / 0 - 20 °C
3.1: sodium tetrahydroborate; acetic acid / 1 h / 20 °C
4.1: triethylamine / dichloromethane / 0.25 h / 0 - 20 °C
4.2: 3 h / Reflux
With
sodium tetrahydroborate; sulfuric acid; iron; potassium carbonate; acetic acid; triethylamine;
In
tetrahydrofuran; ethanol; dichloromethane; water; N,N-dimethyl-formamide;
