Phenprobamate

Base Information

Chemical Name:Phenprobamate
CAS No.:673-31-4
Molecular Formula:C10H13 N O2
Molecular Weight:179.219
Hs Code.:2924299090
European Community (EC) Number:211-606-1
NSC Number:64270,50538,44682
UNII:UJZ473TPS0
DSSTox Substance ID:DTXSID2046464
Nikkaji Number:J3.316B
Wikipedia:Phenprobamate
Wikidata:Q7181402
NCI Thesaurus Code:C98239
Metabolomics Workbench ID:121617
ChEMBL ID:CHEMBL1079576
Mol file:673-31-4.mol

Synonyms:3-phenylpropylcarbamate;Gamaquil;phenprobamate

Suppliers and Price of Phenprobamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Phenprobamate
5g
$ 50.00

Chemenu
3-phenylpropylcarbamate 95+%
25g
$ 804.00

Chemenu
3-phenylpropylcarbamate 95+%
5g
$ 252.00

Chemenu
3-phenylpropylcarbamate 95+%
10g
$ 402.00

Biosynth Carbosynth
Phenprobamate
100 mg
$ 50.00

AvaChem
Phenprobamate
1g
$ 95.00

AvaChem
Phenprobamate
100mg
$ 45.00

AvaChem
Phenprobamate
10g
$ 389.00

American Custom Chemicals Corporation
PHENPROBAMATE 95.00%
25MG
$ 154.35

Alichem
3-Phenylpropylcarbamate
5g
$ 275.40

Total 114 raw suppliers

Chemical Property of Phenprobamate

Chemical Property:

Vapor Pressure:4.69E-05mmHg at 25°C
Melting Point:101-104°
Refractive Index:1.5710 (estimate)
Boiling Point:349.5oC at 760 mmHg
PKA:13.47±0.50(Predicted)
Flash Point:183.1oC
PSA：52.32000
Density:1.103g/cm3
LogP:2.41480
Storage Temp.:Sealed in dry,Room Temperature
Solubility.:Chloroform (Slightly), Methanol (Slightly)
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:179.094628657
Heavy Atom Count:13
Complexity:153

Purity/Quality:

99% ^*data from raw suppliers

Phenprobamate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CCCOC(=O)N
Uses Phenprobamate (3-phenylpropylcarbamate) is a centrally acting muscle relaxant with mild sedative and anticonvulsant effects. Muscle relaxants can enhance and prolong the effect of narcotic drugs and enable to obtain same effect with a smaller amount of alcohol or illicit substance.

Technology Process of Phenprobamate

There total 8 articles about Phenprobamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 122-97-4
3-Phenyl-1-propanol

: 622-46-8
carbamic acid phenyl ester

: 673-31-4
phenprobamate

Guidance literature:: With di-n-butyltin maleate; In toluene; at 90 ℃; for 4h;
DOI:10.1055/s-0030-1258102

Reference yield: 98.0%

: 122-97-4
3-Phenyl-1-propanol

: 598-55-0
methyl carbamate

: 673-31-4
phenprobamate

Guidance literature:: With di-n-butyltin maleate; In toluene; for 3h; Reflux;
DOI:10.1055/s-0040-1708020

Reference yield:

: 3-phenylpropyl hydroxycarbamate

: 673-31-4
phenprobamate

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / diethyl ether / 12 h / 0 - 20 °C

2: tris(2,2-bipyridine)ruthenium(II) hexafluorophosphate; potassium carbonate / 12 h / 25 °C / Inert atmosphere; Irradiation

With tris(2,2-bipyridine)ruthenium(II) hexafluorophosphate; potassium carbonate; In diethyl ether;
DOI:10.1021/jacs.0c00868