(1S,2S,3R,4S)-4-(phenylmethoxy)-3-[(phenylmethoxy)methyl]-2-(phenylseleno)cyclopentan-1-ol

Base Information

• Chemical Name: (1S,2S,3R,4S)-4-(phenylmethoxy)-3-[(phenylmethoxy)methyl]-2-(phenylseleno)cyclopentan-1-ol
• CAS No.: 259659-50-2
• Molecular Formula: C₂₆H₂₈O₃Se
• Molecular Weight: 467.467
• Mol file: 259659-50-2.mol

Synonyms:(1S,2S,3R,4S)-4-(phenylmethoxy)-3-[(phenylmethoxy)methyl]-2-(phenylseleno)cyclopentan-1-ol

Chemical Property of (1S,2S,3R,4S)-4-(phenylmethoxy)-3-[(phenylmethoxy)methyl]-2-(phenylseleno)cyclopentan-1-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1S,2S,3R,4S)-4-(phenylmethoxy)-3-[(phenylmethoxy)methyl]-2-(phenylseleno)cyclopentan-1-ol

There total 3 articles about (1S,2S,3R,4S)-4-(phenylmethoxy)-3-[(phenylmethoxy)methyl]-2-(phenylseleno)cyclopentan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Trifluoro-acetic acid (1S,2S,3R,4S)-4-benzyloxy-3-benzyloxymethyl-2-phenylselanyl-cyclopentyl ester → (1S,2S,3R,4S)-4-(phenylmethoxy)-3-[(phenylmethoxy)methyl]-2-(phenylseleno)cyclopentan-1-ol (259659-50-2)

Guidance literature:

With potassium hydroxide; In ethanol; for 0.25h;

DOI:10.1002/(SICI)1522-2675(19991215)82:12<2119::AID-HLCA2119>3.0.CO;2-Y

Reference yield:

Phenylselenyl chloride (5707-04-0) → (1S,2S,3R,4S)-4-(phenylmethoxy)-3-[(phenylmethoxy)methyl]-2-(phenylseleno)cyclopentan-1-ol (259659-50-2)

Guidance literature:

Multi-step reaction with 2 steps

1: dimethylsulfoxide / 1 h

2: KOH / ethanol / 0.25 h

With potassium hydroxide; In ethanol; dimethyl sulfoxide; 1: Substitution / 2: Hydrolysis;

DOI:10.1002/(SICI)1522-2675(19991215)82:12<2119::AID-HLCA2119>3.0.CO;2-Y

Reference yield:

(3R,4S)-4-(phenylmethoxy)-3-[(phenylmethoxy)methyl]cyclopent-1-ene (191480-69-0) → (1S,2S,3R,4S)-4-(phenylmethoxy)-3-[(phenylmethoxy)methyl]-2-(phenylseleno)cyclopentan-1-ol (259659-50-2)

Guidance literature:

Multi-step reaction with 2 steps

1: dimethylsulfoxide / 1 h

2: KOH / ethanol / 0.25 h

With potassium hydroxide; In ethanol; dimethyl sulfoxide; 1: Substitution / 2: Hydrolysis;

DOI:10.1002/(SICI)1522-2675(19991215)82:12<2119::AID-HLCA2119>3.0.CO;2-Y

upstream raw materials:

Phenylselenyl chloride

(3R,4S)-4-(phenylmethoxy)-3-[(phenylmethoxy)methyl]cyclopent-1-ene

Downstream raw materials:

(1S,4S)-4-(phenylmethoxy)-3-[(phenylmethoxy)methyl]cyclopent-2-en-1-ol

(1R,4S)-4-(phenylmethoxy)-3-[(phenylmethoxy)methyl]cyclopent-2-en-1-ol

(1S,2R,4S,5R)-4-(phenylmethoxy)-5-[(phenylmethoxy)methyl]bicyclo[3.1.0]hexan-2-ol

(1R,4S)-4-(phenylmethoxy)-3-[(phenylmethoxy)methyl]cyclopent-2-enyl benzoate