(7S,10S)-10-[(tert-butoxycarbonyl)(ethyl)amino]-2-{[(4-fluorobenzyl)amino]carbonyl}-7-methoxy-4-oxo-4,6,7,8,9,10-hexahydropyrimido[1,2-a]azepin-3-yl methanesulfonate

Base Information

Chemical Name:(7S,10S)-10-[(tert-butoxycarbonyl)(ethyl)amino]-2-{[(4-fluorobenzyl)amino]carbonyl}-7-methoxy-4-oxo-4,6,7,8,9,10-hexahydropyrimido[1,2-a]azepin-3-yl methanesulfonate
CAS No.:1220511-12-5
Molecular Formula:C₂₆H₃₅FN₄O₈S
Molecular Weight:582.65
Hs Code.:

(7S,10S)-10-[(tert-butoxycarbonyl)(ethyl)amino]-2-{[(4-fluorobenzyl)amino]carbonyl}-7-methoxy-4-oxo-4,6,7,8,9,10-hexahydropyrimido[1,2-a]azepin-3-yl methanesulfonate

Synonyms:(7S,10S)-10-[(tert-butoxycarbonyl)(ethyl)amino]-2-{[(4-fluorobenzyl)amino]carbonyl}-7-methoxy-4-oxo-4,6,7,8,9,10-hexahydropyrimido[1,2-a]azepin-3-yl methanesulfonate

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Chemical Property of (7S,10S)-10-[(tert-butoxycarbonyl)(ethyl)amino]-2-{[(4-fluorobenzyl)amino]carbonyl}-7-methoxy-4-oxo-4,6,7,8,9,10-hexahydropyrimido[1,2-a]azepin-3-yl methanesulfonate

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Technology Process of (7S,10S)-10-[(tert-butoxycarbonyl)(ethyl)amino]-2-{[(4-fluorobenzyl)amino]carbonyl}-7-methoxy-4-oxo-4,6,7,8,9,10-hexahydropyrimido[1,2-a]azepin-3-yl methanesulfonate

There total 1 articles about (7S,10S)-10-[(tert-butoxycarbonyl)(ethyl)amino]-2-{[(4-fluorobenzyl)amino]carbonyl}-7-methoxy-4-oxo-4,6,7,8,9,10-hexahydropyrimido[1,2-a]azepin-3-yl methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

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: 1220511-11-4
2-{(4S)-1-[(tert-butoxycarbonyl)(ethyl)amino]-4-methoxy-5-[(methylsulfonyl)oxy]pentyl}-6-{[(4-fluorobenzyl)amino]carbonyl}pyrimidine-4,5-diyl dimethanesulfonate

: 1220511-12-5
(7S,10S)-10-[(tert-butoxycarbonyl)(ethyl)amino]-2-{[(4-fluorobenzyl)amino]carbonyl}-7-methoxy-4-oxo-4,6,7,8,9,10-hexahydropyrimido[1,2-a]azepin-3-yl methanesulfonate

: 1220511-13-6
(7S,10R)-10-[(tert-butoxycarbonyl)(ethyl)amino]-2-{[(4-fluorobenzyl)amino]carbonyl}-7-methoxy-4-oxo-4,6,7,8,9,10-hexahydropyrimido[1,2-a]azepin-3-yl methanesulfonate

Guidance literature:: 2-{(4S)-1-[(tert-butoxycarbonyl)(ethyl)amino]-4-methoxy-5-[(methylsulfonyl)oxy]pentyl}-6-{[(4-fluorobenzyl)amino]carbonyl}pyrimidine-4,5-diyl dimethanesulfonate; With caesium carbonate; In N,N-dimethyl-formamide; at 100 ℃; for 1h;

With methanesulfonyl chloride; In N,N-dimethyl-formamide; at 0 ℃; for 0.333333h;