5,6-Dichlorobenzotriazole

Base Information

• Chemical Name: 5,6-Dichlorobenzotriazole
• CAS No.: 34374-67-9
• Molecular Formula: C6H3 Cl2 N3
• Molecular Weight: 188.016
• Hs Code.: 2933990090
• Mol file: 34374-67-9.mol

Synonyms:Benzotriazole,5,6-dichloro- (6CI,7CI); 5,6-Dichloro-1H-benzotriazole;5,6-Dichlorobenzotriazole; NSC 90977

Chemical Property of 5,6-Dichlorobenzotriazole

Chemical Property:

• Vapor Pressure: 3.66E-05mmHg at 25°C
• Melting Point: 264 °C
• Boiling Point: 353.1°Cat760mmHg
• PKA: 6.56±0.40(Predicted)
• Flash Point: 198.5°C
• PSA: 41.57000
• Density: 1.675g/cm³
• LogP: 2.26470

Purity/Quality:

99% ^*data from raw suppliers

5,6-dichloro-1H-1,2,3-benzotriazole ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5,6-Dichlorobenzotriazole

There total 6 articles about 5,6-Dichlorobenzotriazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

4,5-Dichloro-1,2-phenylenediamine (5348-42-5) → 5,6-dichloro-1H-benzo[d][1,2,3]triazole (34374-67-9)

Guidance literature:

With K₁₀ Montmorillonite Clay; sodium nitrite; In neat (no solvent, solid phase); at 150 ℃; for 1h; Microwave irradiation; Green chemistry;

DOI:10.1039/c7gc00901a

Reference yield: 72.0%

5,6-dichloro-1-hydroxy-1H-benzotriazole (26280-84-2) → 5,6-dichloro-1H-benzo[d][1,2,3]triazole (34374-67-9)

Guidance literature:

5,6-dichloro-1-hydroxy-1H-benzotriazole; With triethylamine; In acetonitrile; at 20 ℃; for 0.5h;

With tetrahydroxyborate; In acetonitrile; at 50 ℃; for 0.5h;

DOI:10.1039/c6ob01170e

Reference yield:

1,2-dichloro-4,5-dinitrobenzene (6306-39-4) → 5,6-dichloro-1H-benzo[d][1,2,3]triazole (34374-67-9)

Guidance literature:

With hydrogenchloride; tin(ll) chloride; und anschliessend mit NaNO₂ in H₂O;

upstream raw materials:

1,2-dichloro-4,5-dinitrobenzene

4,5-Dichloro-1,2-phenylenediamine

5,6-dichloro-1-hydroxy-1H-benzotriazole

2,4,5-Trichloronitrobenzene

Downstream raw materials:

(E)-2-(5,6-dichloro-1H-benzo[d][1,2,3]triazol-1-yl)-3-p-tolylacrylonitrile

(E)-2-(5,6-dichloro-1H-benzo[d][1,2,3]triazol-1-yl)-3-(4-methoxyphenyl)acrylonitrile

5,6-Dichloro-2-<2'-deoxy-3',5'-di-O-(4-toluoyl)-β-D-erythro-pentofuranosyl>-2H-benzotriazole

5,6-Dichloro-1-<2'-deoxy-3',5'-di-O-(4-toluoyl)-β-D-erythro-pentofuranosyl>-1H-benzotriazole

Refernces

• 1、 Akulov, Alexey A.,Varaksin, Mikhail V.,Tsmokalyuk, Anton N.,Charushin, Valery N.,Chupakhin, Oleg N.. "Blue-light-promoted radical C-H azolation of cyclic nitrones enabled by Selectfluor". supporting information. p. 2049 - 2057. Retrieved 2021/03/26.
• 2、 Szymaniec-Rutkowska, Anna,Bugajska, Ewa,Kasperowicz, S?awomir,Mieczkowska, Kinga,Maciejewska, Agnieszka M.,Poznański, Jaros?aw. "Does the partial molar volume of a solute reflect the free energy of hydrophobic solvation?". . . Retrieved 2019/08/26.