diethyl (4R)-2-methylene-4-{(2R)-1-[(1S)-phenylethyl]piperidin-2-yl}pentanedioate

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Chemical Name:diethyl (4R)-2-methylene-4-{(2R)-1-[(1S)-phenylethyl]piperidin-2-yl}pentanedioate
CAS No.:1000291-99-5
Molecular Formula:C₂₃H₃₃NO₄
Molecular Weight:387.519
Hs Code.:

Synonyms:diethyl (4R)-2-methylene-4-{(2R)-1-[(1S)-phenylethyl]piperidin-2-yl}pentanedioate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of diethyl (4R)-2-methylene-4-{(2R)-1-[(1S)-phenylethyl]piperidin-2-yl}pentanedioate

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Technology Process of diethyl (4R)-2-methylene-4-{(2R)-1-[(1S)-phenylethyl]piperidin-2-yl}pentanedioate

There total 1 articles about diethyl (4R)-2-methylene-4-{(2R)-1-[(1S)-phenylethyl]piperidin-2-yl}pentanedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 254427-95-7
ethyl {(2R)-1-[(1S)-1-phenylethyl]piperidin-2-yl}acetate

: 17435-72-2
ethyl 2-bromomethyl-2-propenoate

: 1000291-99-5
diethyl (4R)-2-methylene-4-{(2R)-1-[(1S)-phenylethyl]piperidin-2-yl}pentanedioate

Guidance literature:: ethyl {(2R)-1-[(1S)-1-phenylethyl]piperidin-2-yl}acetate; With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 1h;

ethyl 2-bromomethyl-2-propenoate; In tetrahydrofuran; Further stages.;
DOI:10.1039/b712503h