bis(4-methoxyphenyl) (R)-2-(4-(4-chlorophenyl)-4-oxobutan-2-yl)malonate

Base Information

• Chemical Name: bis(4-methoxyphenyl) (R)-2-(4-(4-chlorophenyl)-4-oxobutan-2-yl)malonate
• CAS No.: 960371-75-9
• Molecular Formula: C₂₇H₂₅ClO₇
• Molecular Weight: 496.944
• Mol file: 960371-75-9.mol

Synonyms:bis(4-methoxyphenyl) (R)-2-(4-(4-chlorophenyl)-4-oxobutan-2-yl)malonate

Chemical Property of bis(4-methoxyphenyl) (R)-2-(4-(4-chlorophenyl)-4-oxobutan-2-yl)malonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of bis(4-methoxyphenyl) (R)-2-(4-(4-chlorophenyl)-4-oxobutan-2-yl)malonate

There total 1 articles about bis(4-methoxyphenyl) (R)-2-(4-(4-chlorophenyl)-4-oxobutan-2-yl)malonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

bis(4-methoxyphenyl) 2-ethylidenemalonate (960371-65-7) + 1-(4-chlorophenyl)ethenylacetamide (208118-80-3) → bis(4-methoxyphenyl) (R)-2-(4-(4-chlorophenyl)-4-oxobutan-2-yl)malonate (960371-75-9) + bis(4-methoxyphenyl) (S)-2-(4-(4-chlorophenyl)-4-oxobutan-2-yl)malonate

Guidance literature:

bis(4-methoxyphenyl) 2-ethylidenemalonate; 1-(4-chlorophenyl)ethenylacetamide; With copper(II) bis(trifluoromethanesulfonate); In dichloromethane; at -78 ℃; for 22h;

With hydrogen bromide; In tetrahydrofuran; at 20 ℃; for 0.025h; Further stages. Title compound not separated from byproducts.;

DOI:10.1002/anie.200702517

upstream raw materials:

bis(4-methoxyphenyl) 2-ethylidenemalonate

1-(4-chlorophenyl)ethenylacetamide