3'-N-(N'-benzyloxycarbonyl-L-phenylalanyl)-3'-deoxy-2',3'-secoadenosine

Base Information

Chemical Name:3'-N-(N'-benzyloxycarbonyl-L-phenylalanyl)-3'-deoxy-2',3'-secoadenosine
CAS No.:119898-90-7
Molecular Formula:C₂₇H₃₁N₇O₆
Molecular Weight:549.586
Hs Code.:

Synonyms:3'-N-(N'-benzyloxycarbonyl-L-phenylalanyl)-3'-deoxy-2',3'-secoadenosine

Suppliers and Price of 3'-N-(N'-benzyloxycarbonyl-L-phenylalanyl)-3'-deoxy-2',3'-secoadenosine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3'-N-(N'-benzyloxycarbonyl-L-phenylalanyl)-3'-deoxy-2',3'-secoadenosine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3'-N-(N'-benzyloxycarbonyl-L-phenylalanyl)-3'-deoxy-2',3'-secoadenosine

There total 10 articles about 3'-N-(N'-benzyloxycarbonyl-L-phenylalanyl)-3'-deoxy-2',3'-secoadenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 1161-13-3
N-Cbz-L-Phe

: 119898-85-0
3'-amino-3'-deoxy-2',3'-secoadenosine

: 119898-90-7
3'-N-(N'-benzyloxycarbonyl-L-phenylalanyl)-3'-deoxy-2',3'-secoadenosine

Guidance literature:: With 1-hydroxy-pyrrolidine-2,5-dione; dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide; 1.) 5 deg C, 30 min 2.) RT;
DOI:10.1016/S0040-4020(01)89829-X

Reference yield:

: 119898-84-9
3'-azido-3'-deoxy-2',3'-secoadenosine

: 119898-90-7
3'-N-(N'-benzyloxycarbonyl-L-phenylalanyl)-3'-deoxy-2',3'-secoadenosine

Guidance literature:: Multi-step reaction with 2 steps

1: 93 percent / H₂ / Pd (10percent on charcoal) / ethanol; H₂O / 72 h

2: 50 percent / N-hydroxysuccinimide, 1,3-N,N-dicyclohexylcarbodiimide / dimethylformamide / 1.) 5 deg C, 30 min 2.) RT

With 1-hydroxy-pyrrolidine-2,5-dione; hydrogen; dicyclohexyl-carbodiimide; 10% palladium on active carbon; In ethanol; water; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)89829-X

Reference yield:

: 119898-65-6
(2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-((tert-butyldiphenylsilyloxy)methyl)tetrahydrofuran-3,4-diol

: 119898-90-7
3'-N-(N'-benzyloxycarbonyl-L-phenylalanyl)-3'-deoxy-2',3'-secoadenosine

Guidance literature:: Multi-step reaction with 9 steps

1: 89 percent / sodium periodate / acetone; H₂O / 15 °C / dark

2: 83 percent / sodium borohydride / ethanol; H₂O / Ambient temperature; dark

3: 80 percent / pyridine / 0 °C

4: 66 percent / lithium azide / dimethylformamide / 48 h / 55 - 60 °C

5: 96 percent / dimethylformamide / 48 h / 95 °C

6: 94 percent / potassium carbonate / methanol / Ambient temperature

7: 87 percent / tetrabutylammonium fluoride / tetrahydrofuran / 2 h / Ambient temperature

8: 93 percent / H₂ / Pd (10percent on charcoal) / ethanol; H₂O / 72 h

9: 50 percent / N-hydroxysuccinimide, 1,3-N,N-dicyclohexylcarbodiimide / dimethylformamide / 1.) 5 deg C, 30 min 2.) RT

With sodium tetrahydroborate; sodium periodate; 1-hydroxy-pyrrolidine-2,5-dione; lithium azide; tetrabutyl ammonium fluoride; hydrogen; potassium carbonate; dicyclohexyl-carbodiimide; 10% palladium on active carbon; In tetrahydrofuran; pyridine; methanol; ethanol; water; N,N-dimethyl-formamide; acetone;
DOI:10.1016/S0040-4020(01)89829-X