Boc-Lys(Cbz)-OC₁₆H₃₃

Base Information

• Chemical Name: Boc-Lys(Cbz)-OC₁₆H₃₃
• CAS No.: 794591-65-4
• Molecular Formula: C₃₅H₆₀N₂O₆
• Molecular Weight: 604.871
• Mol file: 794591-65-4.mol

Synonyms:Boc-Lys(Cbz)-OC₁₆H₃₃

Chemical Property of Boc-Lys(Cbz)-OC₁₆H₃₃

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of Boc-Lys(Cbz)-OC₁₆H₃₃

There total 1 articles about Boc-Lys(Cbz)-OC₁₆H₃₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

1-Hexadecanol (36653-82-4,124-29-8) + Boc-Lys(Z)-OH (2389-45-9) → Boc-Lys(Cbz)-OC16H33 (794591-65-4)

Guidance literature:

With dmap; dacarbazine; In dichloromethane; at 0 - 20 ℃; for 17h;

DOI:10.1016/j.bmc.2004.07.035

Reference yield:

Boc-Lys(Cbz)-OC16H33 (794591-65-4) → N-succinyl-Lysinv(Cbz)-OC16H33

Guidance literature:

Multi-step reaction with 2 steps

1: CH₂Cl₂ / 1 h / 20 °C

2: 782 mg / TEA / CHCl₃; tetrahydrofuran / 16 h / 20 °C

With TEA; In tetrahydrofuran; dichloromethane; chloroform;

DOI:10.1016/j.bmc.2004.07.035

Reference yield:

Boc-Lys(Cbz)-OC16H33 (794591-65-4) + trifluoroacetic acid (76-05-1) → Lysinv(Cbz)-OC16H33 (3392-30-1)

Guidance literature:

In dichloromethane; at 20 ℃; for 1h;

DOI:10.1016/j.bmc.2004.07.035

upstream raw materials:

1-Hexadecanol

Boc-Lys(Z)-OH

Downstream raw materials:

Lys^inv(Cbz)-OC₁₆H₃₃