(S)-5-Acetylamino-2-[methyl-(toluene-4-sulfonyl)-amino]-pentanoic acid isopropyl ester

Base Information

Chemical Name:(S)-5-Acetylamino-2-[methyl-(toluene-4-sulfonyl)-amino]-pentanoic acid isopropyl ester
CAS No.:124312-52-3
Molecular Formula:C₁₈H₂₈N₂O₅S
Molecular Weight:384.497
Hs Code.:

Synonyms:(S)-5-Acetylamino-2-[methyl-(toluene-4-sulfonyl)-amino]-pentanoic acid isopropyl ester

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Chemical Property of (S)-5-Acetylamino-2-[methyl-(toluene-4-sulfonyl)-amino]-pentanoic acid isopropyl ester

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Technology Process of (S)-5-Acetylamino-2-[methyl-(toluene-4-sulfonyl)-amino]-pentanoic acid isopropyl ester

There total 1 articles about (S)-5-Acetylamino-2-[methyl-(toluene-4-sulfonyl)-amino]-pentanoic acid isopropyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 34605-48-6
N^α-Acetyl-N^α-tosyl-L-ornithine-isopropylester

: 77-78-1
dimethyl sulfate

: 124312-52-3
(S)-5-Acetylamino-2-[methyl-(toluene-4-sulfonyl)-amino]-pentanoic acid isopropyl ester

Guidance literature:: With sodium hydroxide; In water; for 4h; Ambient temperature; detergent;

Reference yield: 88.0%

: 124312-52-3
(S)-5-Acetylamino-2-[methyl-(toluene-4-sulfonyl)-amino]-pentanoic acid isopropyl ester

: 101-83-7
N-cyclohexyl-cyclohexanamine

: 124312-57-8
(S)-5-tert-Butoxycarbonylamino-2-[methyl-(toluene-4-sulfonyl)-amino]-pentanoic acid; compound with dicyclohexyl-amine

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; water; for 4h; Heating;

Reference yield:

: 124312-52-3
(S)-5-Acetylamino-2-[methyl-(toluene-4-sulfonyl)-amino]-pentanoic acid isopropyl ester

: 124337-32-2
{(S)-4-Methylcarbamoyl-4-[methyl-(toluene-4-sulfonyl)-amino]-butyl}-carbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 88 percent / HCl / H₂O; dioxane / 4 h / Heating

2: 73 percent / 1-hydroxybenzotriazole, DCC / dimethylformamide / 1. -12 deg C, 30 min; 2. 0 deg C, 2 h; 3. 5 deg c, 18 h

With hydrogenchloride; benzotriazol-1-ol; dicyclohexyl-carbodiimide; In 1,4-dioxane; water; N,N-dimethyl-formamide;