1-benzylthio-3-diphenylphosphanyl-2-diphenylphosphanylmethyl-2-methylpropane

Base Information

• Chemical Name: 1-benzylthio-3-diphenylphosphanyl-2-diphenylphosphanylmethyl-2-methylpropane
• CAS No.: 175222-33-0
• Molecular Formula: C₃₆H₃₆P₂S
• Molecular Weight: 562.695
• Mol file: 175222-33-0.mol

Synonyms:1-benzylthio-3-diphenylphosphanyl-2-diphenylphosphanylmethyl-2-methylpropane

Chemical Property of 1-benzylthio-3-diphenylphosphanyl-2-diphenylphosphanylmethyl-2-methylpropane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-benzylthio-3-diphenylphosphanyl-2-diphenylphosphanylmethyl-2-methylpropane

There total 2 articles about 1-benzylthio-3-diphenylphosphanyl-2-diphenylphosphanylmethyl-2-methylpropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

phenylmethanethiol (100-53-8) + methyl(2-methyldiphenylphosphino)-1-chloro-3-diphenylphosphinopropane (155932-48-2) → 1-benzylthio-3-diphenylphosphanyl-2-diphenylphosphanylmethyl-2-methylpropane (175222-33-0)

Guidance literature:

With potassium tert-butylate; In dimethyl sulfoxide; at 100 ℃; for 4h;

DOI:10.1002/cber.19961290119

Reference yield:

2-(Brommethyl)-2-(chlormethyl)-1-(methylsulfonyloxy)propan (175222-31-8) → 1-benzylthio-3-diphenylphosphanyl-2-diphenylphosphanylmethyl-2-methylpropane (175222-33-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 55 percent / 2.2 M nBuLi / hexane; tetrahydrofuran / 1) -40 deg C, 2 h, 2) -20 deg C, 2 h, to r.t., 18 h

2: 95 percent / KOtBu / dimethylsulfoxide / 4 h / 100 °C

With n-butyllithium; potassium tert-butylate; In tetrahydrofuran; hexane; dimethyl sulfoxide;

DOI:10.1002/cber.19961290119

Reference yield: 71.0%

1-benzylthio-3-diphenylphosphanyl-2-diphenylphosphanylmethyl-2-methylpropane (175222-33-0) → 3-diphenylphosphanyl-2-diphenylphosphanylmethyl-2-methyl-1-propanethiol (161202-62-6)

Guidance literature:

With ammonia; lithium; In tetrahydrofuran; at -50 ℃; for 4h;

DOI:10.1002/cber.19961290119

upstream raw materials:

phenylmethanethiol

methyl(2-methyldiphenylphosphino)-1-chloro-3-diphenylphosphinopropane

2-(Brommethyl)-2-(chlormethyl)-1-(methylsulfonyloxy)propan

Downstream raw materials:

3-diphenylphosphanyl-2-diphenylphosphanylmethyl-2-methyl-1-propanethiol

[1-benzylthio-3-diphenylphosphanyl-2-diphenylphosphanylmethyl-2-methylpropane](1,2-phenylenediamido)cobalt(III) tetrafluoroborate

[1-benzylthio-3-diphenylphosphanyl-2-diphenylphosphanylmethyl-2-methylpropane](2-mercaptophenolato)cobalt(III) tetrafluoroborate

(1,2-benzenedithiolato)-[1-benzylthio-3-diphenylphosphanyl-2-diphenylphosphanylmethyl-2-methylpropane]cobalt(II)