4-(2-tert-Butoxycarbonylamino-3-hydroxy-propyl)-benzoic acid tert-butyl ester

Base Information

Chemical Name:4-(2-tert-Butoxycarbonylamino-3-hydroxy-propyl)-benzoic acid tert-butyl ester
CAS No.:156143-63-4
Molecular Formula:C₁₉H₂₉NO₅
Molecular Weight:351.443
Hs Code.:

Synonyms:4-(2-tert-Butoxycarbonylamino-3-hydroxy-propyl)-benzoic acid tert-butyl ester

Suppliers and Price of 4-(2-tert-Butoxycarbonylamino-3-hydroxy-propyl)-benzoic acid tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-(2-tert-Butoxycarbonylamino-3-hydroxy-propyl)-benzoic acid tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-(2-tert-Butoxycarbonylamino-3-hydroxy-propyl)-benzoic acid tert-butyl ester

There total 5 articles about 4-(2-tert-Butoxycarbonylamino-3-hydroxy-propyl)-benzoic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

: 156143-62-3
4-(2-tert-Butoxycarbonylamino-2-ethoxycarbonyl-ethyl)-benzoic acid tert-butyl ester

: 156143-63-4
4-(2-tert-Butoxycarbonylamino-3-hydroxy-propyl)-benzoic acid tert-butyl ester

Guidance literature:: With sodium tetrahydroborate; In ethanol; water; at 50 ℃; for 4h;
DOI:10.1021/jm00035a014

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 156143-63-4
4-(2-tert-Butoxycarbonylamino-3-hydroxy-propyl)-benzoic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / dimethylformamide

2: 42 percent / NaBH₄ / ethanol; H₂O / 4 h / 50 °C

With sodium tetrahydroborate; In ethanol; water; N,N-dimethyl-formamide;
DOI:10.1021/jm00035a014

Reference yield:

: 108052-76-2
4-(bromomethyl)benzoic acid 1,1-dimethylethyl ester

: 156143-63-4
4-(2-tert-Butoxycarbonylamino-3-hydroxy-propyl)-benzoic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 92 percent / KI, benzyltrimethylammonium hydroxide / dioxane; H₂O / 3 h / Ambient temperature

2: 50 percent / 1 N aq. HCl / diethyl ether / 4 h / Ambient temperature

3: 92 percent / dimethylformamide

4: 42 percent / NaBH₄ / ethanol; H₂O / 4 h / 50 °C

With hydrogenchloride; sodium tetrahydroborate; N-benzyl-trimethylammonium hydroxide; potassium iodide; In 1,4-dioxane; diethyl ether; ethanol; water; N,N-dimethyl-formamide;
DOI:10.1021/jm00035a014