1R-<1α(αR^*,βS^*),2β,5α>-(+/-)-tert-butyl 5-bromo-α-ethenyl-2-hydroxy-2,6,6-trimethyl-β-(4-nitrobenzoyloxy)cyclohexanebutanoate

Base Information

• Chemical Name: 1R-<1α(αR^*,βS^*),2β,5α>-(+/-)-tert-butyl 5-bromo-α-ethenyl-2-hydroxy-2,6,6-trimethyl-β-(4-nitrobenzoyloxy)cyclohexanebutanoate
• CAS No.: 83289-72-9
• Molecular Formula: C₂₆H₃₆BrNO₇
• Molecular Weight: 554.478

Synonyms:1R-<1α(αR^*,βS^*),2β,5α>-(+/-)-tert-butyl 5-bromo-α-ethenyl-2-hydroxy-2,6,6-trimethyl-β-(4-nitrobenzoyloxy)cyclohexanebutanoate

Chemical Property of 1R-<1α(αR^*,βS^*),2β,5α>-(+/-)-tert-butyl 5-bromo-α-ethenyl-2-hydroxy-2,6,6-trimethyl-β-(4-nitrobenzoyloxy)cyclohexanebutanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1R-<1α(αR^*,βS^*),2β,5α>-(+/-)-tert-butyl 5-bromo-α-ethenyl-2-hydroxy-2,6,6-trimethyl-β-(4-nitrobenzoyloxy)cyclohexanebutanoate

There total 4 articles about 1R-<1α(αR^*,βS^*),2β,5α>-(+/-)-tert-butyl 5-bromo-α-ethenyl-2-hydroxy-2,6,6-trimethyl-β-(4-nitrobenzoyloxy)cyclohexanebutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

4-nitro-benzoyl chloride (122-04-3) + 1R-<1α(αR*,βS*),2β,5α>-(+/-)-tert-butyl 5-bromo-α-ethenyl-β,2-dihydroxy-2,6,6-trimethylcyclohexanebutanoate (83289-28-5) → 1R-<1α(αR*,βS*),2β,5α>-(+/-)-tert-butyl 5-bromo-α-ethenyl-2-hydroxy-2,6,6-trimethyl-β-(4-nitrobenzoyloxy)cyclohexanebutanoate (83289-72-9)

Guidance literature:

With dmap; In pyridine; dichloromethane; for 0.5h;

DOI:10.1021/ja00388a038

Reference yield:

tert-butyl (E)-crotonate (79218-15-8) → 1R-<1α(αR*,βS*),2β,5α>-(+/-)-tert-butyl 5-bromo-α-ethenyl-2-hydroxy-2,6,6-trimethyl-β-(4-nitrobenzoyloxy)cyclohexanebutanoate (83289-72-9)

Guidance literature:

Multi-step reaction with 3 steps

1: LDA

2: LDA / hexamethylphosphoric acid triamide

3: 92 percent / 4-(dimethylamino)pyridine / CH₂Cl₂; pyridine / 0.5 h

With dmap; lithium diisopropyl amide; In pyridine; N,N,N,N,N,N-hexamethylphosphoric triamide; dichloromethane;

DOI:10.1021/ja00388a038

Reference yield:

t-butyl vinylacetate (14036-55-6) → 1R-<1α(αR*,βS*),2β,5α>-(+/-)-tert-butyl 5-bromo-α-ethenyl-2-hydroxy-2,6,6-trimethyl-β-(4-nitrobenzoyloxy)cyclohexanebutanoate (83289-72-9)

Guidance literature:

Multi-step reaction with 3 steps

1: LDA

2: LDA / hexamethylphosphoric acid triamide

3: 92 percent / 4-(dimethylamino)pyridine / CH₂Cl₂; pyridine / 0.5 h

With dmap; lithium diisopropyl amide; In pyridine; N,N,N,N,N,N-hexamethylphosphoric triamide; dichloromethane;

DOI:10.1021/ja00388a038

upstream raw materials:

4-nitro-benzoyl chloride

1R-<1α(αR^*,βS^*),2β,5α>-(+/-)-tert-butyl 5-bromo-α-ethenyl-β,2-dihydroxy-2,6,6-trimethylcyclohexanebutanoate

t-butyl vinylacetate

tert-butyl (E)-crotonate

Downstream raw materials:

(2α,3β,4β,5aβ,7α,9aα)-(+/-)-7-bromo-2-(bromomethyl)decahydro-6,6,9a-trimethyl-4-(4-nitrobenzoyloxy)-1-benzoxepin-3-carboxylic acid

(3aα,4aβ,7β,8aα,10α,10aβ)-(+/-)-7-bromodecahydro-4a,8,8-trimethyl-10-(4-nitrobenzoyloxy)furo<3,4-b>-1-benzoxepin-1(3H)-one

(2α,3β,4β,5aβ,7α,9aα)-(+/-)-tert-butyl 7-bromo-2-(bromomethyl)decahydro-6,6,9a-trimethyl-4-(4-nitrobenzoyloxy)-1-benzoxepin-3-carboxylate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 83289-72-9 1R-<1α(αR^*,βS^*),2β,5α>-(+/-)-tert-butyl 5-bromo-α-ethenyl-2-hydroxy-2,6,6-trimethyl-β-(4-nitrobenzoyloxy)cyclohexanebutanoate

Send

Send

Metric Ton KG G Pound L ML

Send

Send