(R)-2-(2-tert-Butoxycarbonylamino-ethylamino)-3-methyl-butyric acid benzyl ester

Base Information

Chemical Name:(R)-2-(2-tert-Butoxycarbonylamino-ethylamino)-3-methyl-butyric acid benzyl ester
CAS No.:1071153-84-8
Molecular Formula:C₁₉H₃₀N₂O₄
Molecular Weight:350.458
Hs Code.:

Synonyms:(R)-2-(2-tert-Butoxycarbonylamino-ethylamino)-3-methyl-butyric acid benzyl ester

Suppliers and Price of (R)-2-(2-tert-Butoxycarbonylamino-ethylamino)-3-methyl-butyric acid benzyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (R)-2-(2-tert-Butoxycarbonylamino-ethylamino)-3-methyl-butyric acid benzyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of (R)-2-(2-tert-Butoxycarbonylamino-ethylamino)-3-methyl-butyric acid benzyl ester

There total 3 articles about (R)-2-(2-tert-Butoxycarbonylamino-ethylamino)-3-methyl-butyric acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 89711-08-0
N-(t-butoxycarbonyl)glycinal

: 46460-17-7
(R)-O-benzyl 2-amino-3-methylbutanoate

: 1071153-84-8
(R)-2-(2-tert-Butoxycarbonylamino-ethylamino)-3-methyl-butyric acid benzyl ester

Guidance literature:: With sodium cyanoborohydride; acetic acid; In methanol; Ambient temperature;
DOI:10.1016/S0040-4039(98)00862-4

Reference yield:

: 100-39-0
benzyl bromide

: 1071153-84-8
(R)-2-(2-tert-Butoxycarbonylamino-ethylamino)-3-methyl-butyric acid benzyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: Cs₂CO₃ / dimethylformamide

2: TFA / Ambient temperature

3: 67 percent / NaBH₃CN, AcOH / methanol / Ambient temperature

With sodium cyanoborohydride; caesium carbonate; acetic acid; trifluoroacetic acid; In methanol; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(98)00862-4

Reference yield:

: 279255-85-5
(R)-O-benzyl 2-N-(t-butoxycarbonyl)amino-3-methylbutanoate

: 1071153-84-8
(R)-2-(2-tert-Butoxycarbonylamino-ethylamino)-3-methyl-butyric acid benzyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: TFA / Ambient temperature

2: 67 percent / NaBH₃CN, AcOH / methanol / Ambient temperature

With sodium cyanoborohydride; acetic acid; trifluoroacetic acid; In methanol;
DOI:10.1016/S0040-4039(98)00862-4