C₁₉H₁₉F₂IN₂O₅S

Base Information

• Chemical Name: C₁₉H₁₉F₂IN₂O₅S
• CAS No.: 1287794-62-0
• Molecular Formula: C₁₉H₁₉F₂IN₂O₅S
• Molecular Weight: 552.338
• Mol file: 1287794-62-0.mol

Synonyms:C₁₉H₁₉F₂IN₂O₅S

Chemical Property of C₁₉H₁₉F₂IN₂O₅S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₉H₁₉F₂IN₂O₅S

There total 7 articles about C₁₉H₁₉F₂IN₂O₅S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C19H17F2IN2O3S (1287794-55-1) → C19H19F2IN2O5S (1287794-62-0)

Guidance literature:

With osmium(VIII) oxide; water; 4-methylmorpholine N-oxide; In tetrahydrofuran; at 20 ℃; for 16h;

Reference yield:

3,4,5-trifluorophenol (99627-05-1) → C19H19F2IN2O5S (1287794-62-0)

Guidance literature:

Multi-step reaction with 7 steps

1.1: nitric acid; acetic acid / 0.75 h / 4 - 20 °C

2.1: potassium carbonate / acetone / 2 h / Reflux

3.1: lithium hexamethyldisilazane / tetrahydrofuran / 1 h / -78 °C

3.2: 17 h / -78 - 20 °C

4.1: water; sodium dithionite / ethanol / 1 h / 90 °C

5.1: 16 h / 50 °C

6.1: Hoveyda-Grubbs catalyst second generation / 1,1-dichloroethane / 3 h / 70 °C

7.1: osmium(VIII) oxide; water; 4-methylmorpholine N-oxide / tetrahydrofuran / 16 h / 20 °C

With osmium(VIII) oxide; sodium dithionite; water; nitric acid; potassium carbonate; acetic acid; 4-methylmorpholine N-oxide; lithium hexamethyldisilazane; Hoveyda-Grubbs catalyst second generation; In tetrahydrofuran; 1,1-dichloroethane; ethanol; acetone;

Reference yield:

phenol, 3,4,5-trifluoro-2-nitro (923033-24-3) → C19H19F2IN2O5S (1287794-62-0)

Guidance literature:

Multi-step reaction with 6 steps

1.1: potassium carbonate / acetone / 2 h / Reflux

2.1: lithium hexamethyldisilazane / tetrahydrofuran / 1 h / -78 °C

2.2: 17 h / -78 - 20 °C

3.1: water; sodium dithionite / ethanol / 1 h / 90 °C

4.1: 16 h / 50 °C

5.1: Hoveyda-Grubbs catalyst second generation / 1,1-dichloroethane / 3 h / 70 °C

6.1: osmium(VIII) oxide; water; 4-methylmorpholine N-oxide / tetrahydrofuran / 16 h / 20 °C

With osmium(VIII) oxide; sodium dithionite; water; potassium carbonate; 4-methylmorpholine N-oxide; lithium hexamethyldisilazane; Hoveyda-Grubbs catalyst second generation; In tetrahydrofuran; 1,1-dichloroethane; ethanol; acetone;

upstream raw materials:

3,4,5-trifluorophenol

phenol, 3,4,5-trifluoro-2-nitro

benzene, 1,2,3-trifluoro-4-nitro-5-(2-propen-1-yloxy)

(3-allyloxy-5,6-difluoro-2-nitrophenyl)-(4-iodophenyl)-amine