(5-Phenyl-1,3,4-oxadiazol-2-yl)methanol

Base Information

• Chemical Name: (5-Phenyl-1,3,4-oxadiazol-2-yl)methanol
• CAS No.: 54014-02-7
• Molecular Formula: C9H8N2O2
• Molecular Weight: 176.175
• Hs Code.: 2934999090
• European Community (EC) Number: 849-784-3
• DSSTox Substance ID: DTXSID10202331
• Wikidata: Q83075598
• ChEMBL ID: CHEMBL4751493
• Mol file: 54014-02-7.mol

Synonyms:(5-phenyl-1,3,4-oxadiazol-2-yl)methanol;54014-02-7;5-Phenyl-1,3,4-oxadiazole-2-methanol;1,3,4-Oxadiazole-2-methanol, 5-phenyl-;2-Hydroxymethyl-5-phenyl-1,3,4-oxadiazole;CHEMBL4751493;DTXSID10202331;BDBM50554497;MFCD01755392;AKOS009590446;BS-38154;LS-99153;CS-0216979;EN300-65170;Z431953302

Chemical Property of (5-Phenyl-1,3,4-oxadiazol-2-yl)methanol

Chemical Property:

• Vapor Pressure: 2.66E-05mmHg at 25°C
• Boiling Point: 343.6°C at 760 mmHg
• PKA: 12.30±0.10(Predicted)
• Flash Point: 161.6°C
• PSA: 59.15000
• Density: 1.278g/cm³
• LogP: 1.22890
• XLogP3: 0.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 176.058577502
• Heavy Atom Count: 13
• Complexity: 160

Purity/Quality:

99%, ^*data from raw suppliers

(5-Phenyl-1,3,4-oxadiazol-2-yl)methanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=NN=C(O2)CO

Technology Process of (5-Phenyl-1,3,4-oxadiazol-2-yl)methanol

There total 4 articles about (5-Phenyl-1,3,4-oxadiazol-2-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

ethyl 5-phenyl-1,3,4-oxadiazole-2-carboxylate (16691-25-1) → (5-phenyl-[1,3,4]oxadiazol-2-yl)-methanol (54014-02-7)

Guidance literature:

With sodium tetrahydroborate; calcium chloride; In ethanol; at 0 - 20 ℃; for 4h;

Reference yield:

benzoic acid hydrazide (613-94-5) → (5-phenyl-[1,3,4]oxadiazol-2-yl)-methanol (54014-02-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: triethylamine / dichloromethane / 8 h / 0 - 20 °C

1.2: 8 h / 20 °C

2.1: calcium chloride; sodium tetrahydroborate / ethanol / 4 h / 0 - 20 °C

With sodium tetrahydroborate; triethylamine; calcium chloride; In ethanol; dichloromethane;

Reference yield:

benzoic acid methyl ester (93-58-3,5705-52-2,80226-58-0) → (5-phenyl-[1,3,4]oxadiazol-2-yl)-methanol (54014-02-7)

Guidance literature:

Multi-step reaction with 3 steps

1.1: hydrazine hydrate / methanol / 8 h / 80 °C

2.1: triethylamine / dichloromethane / 8 h / 0 - 20 °C

2.2: 8 h / 20 °C

3.1: calcium chloride; sodium tetrahydroborate / ethanol / 4 h / 0 - 20 °C

With sodium tetrahydroborate; hydrazine hydrate; triethylamine; calcium chloride; In methanol; ethanol; dichloromethane;

upstream raw materials:

benzoic acid hydrazide

benzoic acid methyl ester

ethyl 5-phenyl-1,3,4-oxadiazole-2-carboxylate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 54014-02-7 5-Phenyl-1,3,4-oxadiazole-2-methanol

Send

Send

Metric Ton KG G Pound L ML

Send

Send