2-(Boc-amino)ethanethiol

Base Information

Chemical Name:2-(Boc-amino)ethanethiol
CAS No.:67385-09-5
Molecular Formula:C7H15 N O2 S
Molecular Weight:177.268
Hs Code.:2930909090
European Community (EC) Number:628-681-5
DSSTox Substance ID:DTXSID50986668
Nikkaji Number:J1.347.856B
Wikidata:Q82974670

Synonyms:N-(tert-butoxycarbonyl)-2-aminoethanethiol;N-Boc-AET

Suppliers and Price of 2-(Boc-amino)ethanethiol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(Boc-amino)ethanthiol(>90%)
25g
$ 400.00

SynQuest Laboratories
2-(Boc-amino)ethanethiol
5 g
$ 157.00

Sigma-Aldrich
2-(Boc-amino)ethanethiol 97%
25ml
$ 255.00

Sigma-Aldrich
2-(Boc-amino)ethanethiol 97%
5ml
$ 73.80

Oakwood
Boc-Cysteamine
5g
$ 35.00

Oakwood
Boc-Cysteamine
1g
$ 20.00

Oakwood
Boc-Cysteamine
25g
$ 110.00

Oakwood
Boc-Cysteamine
100g
$ 420.00

Matrix Scientific
tert-Butyl N-(2-mercaptoethyl)carbamate
100g
$ 425.00

Matrix Scientific
tert-Butyl N-(2-mercaptoethyl)carbamate
25g
$ 165.00

Total 29 raw suppliers

Chemical Property of 2-(Boc-amino)ethanethiol

Chemical Property:

Vapor Pressure:0.0106mmHg at 25°C
Refractive Index:n20/D 1.474(lit.)
Boiling Point:68 °C0.3 mm Hg(lit.)
PKA:9.95±0.10(Predicted)
Flash Point:>230 °F
PSA：77.13000
Density:1.049 g/mL at 20 °C(lit.)
LogP:1.83180
Storage Temp.:Hygroscopic, Refrigerator, under inert atmosphere
Solubility.:Chloroform (Sparingly), Ethyl Acetate (Slightly)
XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:177.08234989
Heavy Atom Count:11
Complexity:131

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-(Boc-amino)ethanthiol(>90%) ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NCCS
Uses 2-(Boc-amino)ethanthiol is used in the synthesis of several organic compounds including a novel, anisamide-targeted cyclodextrin nanoformulation for the delivery of siRNA to prostate cancer cells which is a potential therapeutic option. Also used in the synthesis of bifunctional azobenzene glycoconjugates for cysteine-based photosensitive cross-linking with bioactive peptides.

Technology Process of 2-(Boc-amino)ethanethiol

There total 11 articles about 2-(Boc-amino)ethanethiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 60-23-1
Cysteamine

: 67385-09-5
2-[(tert-butoxycarbonyl)amino]-1-ethanethiol

Guidance literature:: In tetrahydrofuran; water; at 20 ℃; for 4h; Inert atmosphere;
DOI:10.1002/anie.201505076

Reference yield: 96.0%

: 67385-10-8
di-tert-butyl(disulfanediylbis(ethane-2,1-diyl))dicarbamate

: 67385-09-5
2-[(tert-butoxycarbonyl)amino]-1-ethanethiol

Guidance literature:: With hydrogen; rhodium hydrido (PEt₃)3 complex; In toluene; for 0.5h; Heating;
DOI:10.1016/j.tetlet.2005.06.169

Reference yield: 95.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 156-57-0
2-mercaptoethylamine hydrochloride

: 67385-09-5
2-[(tert-butoxycarbonyl)amino]-1-ethanethiol

Guidance literature:: 2-mercaptoethylamine hydrochloride; With sodium hydride; In tetrahydrofuran; at 0 - 20 ℃;

di-tert-butyl dicarbonate; In tetrahydrofuran; at 0 - 20 ℃;
DOI:10.1081/SCC-120004152