N^α-<(RS)-α-(methoxycarbonyl)-β-phenylpropionyl>-L-α,β-diaminopropionic acid

Base Information

• Chemical Name: N^α-<(RS)-α-(methoxycarbonyl)-β-phenylpropionyl>-L-α,β-diaminopropionic acid
• CAS No.: 72594-79-7
• Molecular Formula: C₁₄H₁₈N₂O₅
• Molecular Weight: 294.307
• Mol file: 72594-79-7.mol

Synonyms:N^α-<(RS)-α-(methoxycarbonyl)-β-phenylpropionyl>-L-α,β-diaminopropionic acid

Chemical Property of N^α-<(RS)-α-(methoxycarbonyl)-β-phenylpropionyl>-L-α,β-diaminopropionic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N^α-<(RS)-α-(methoxycarbonyl)-β-phenylpropionyl>-L-α,β-diaminopropionic acid

There total 2 articles about N^α-<(RS)-α-(methoxycarbonyl)-β-phenylpropionyl>-L-α,β-diaminopropionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzyl Nβ-(benzyloxycarbonyl)-Nα-<(RS)-α-(methoxycarbonyl)-β-phenylpropionyl>-L-α,β-diaminopropionate (72594-83-3) → Nα-<(RS)-α-(methoxycarbonyl)-β-phenylpropionyl>-L-α,β-diaminopropionic acid (72594-79-7)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; water; acetic acid; for 4h; under 2068.6 Torr;

DOI:10.1021/jm00178a012

Reference yield:

2-benzyl-3-methoxy-3-oxopropanoic acid (54561-75-0) → Nα-<(RS)-α-(methoxycarbonyl)-β-phenylpropionyl>-L-α,β-diaminopropionic acid (72594-79-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 76 percent / dicyclohexylcarbodiimide / CH₂Cl₂ / 0 - 20 °C

2: 45 mg / H₂ / 10percent Pd/C / methanol; H₂O; acetic acid / 4 h / 2068.6 Torr

With hydrogen; dicyclohexyl-carbodiimide; palladium on activated charcoal; In methanol; dichloromethane; water; acetic acid;

DOI:10.1021/jm00178a012

upstream raw materials:

benzyl N^β-(benzyloxycarbonyl)-N^α-<(RS)-α-(methoxycarbonyl)-β-phenylpropionyl>-L-α,β-diaminopropionate

2-benzyl-3-methoxy-3-oxopropanoic acid