(2R,3R,4R,5S)-5-Phenyl-3-((4S,5S)-1,3,4,5-tetraphenyl-imidazolidin-2-yl)-1-(toluene-4-sulfonyl)-pyrrolidine-2,4-dicarboxylic acid 2-tert-butyl ester 4-methyl ester

Base Information

Chemical Name:(2R,3R,4R,5S)-5-Phenyl-3-((4S,5S)-1,3,4,5-tetraphenyl-imidazolidin-2-yl)-1-(toluene-4-sulfonyl)-pyrrolidine-2,4-dicarboxylic acid 2-tert-butyl ester 4-methyl ester
CAS No.:135075-70-6
Molecular Formula:C₅₁H₅₁N₃O₆S
Molecular Weight:834.048
Hs Code.:

(2R,3R,4R,5S)-5-Phenyl-3-((4S,5S)-1,3,4,5-tetraphenyl-imidazolidin-2-yl)-1-(toluene-4-sulfonyl)-pyrrolidine-2,4-dicarboxylic acid 2-tert-butyl ester 4-methyl ester

Synonyms:(2R,3R,4R,5S)-5-Phenyl-3-((4S,5S)-1,3,4,5-tetraphenyl-imidazolidin-2-yl)-1-(toluene-4-sulfonyl)-pyrrolidine-2,4-dicarboxylic acid 2-tert-butyl ester 4-methyl ester

Suppliers and Price of (2R,3R,4R,5S)-5-Phenyl-3-((4S,5S)-1,3,4,5-tetraphenyl-imidazolidin-2-yl)-1-(toluene-4-sulfonyl)-pyrrolidine-2,4-dicarboxylic acid 2-tert-butyl ester 4-methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2R,3R,4R,5S)-5-Phenyl-3-((4S,5S)-1,3,4,5-tetraphenyl-imidazolidin-2-yl)-1-(toluene-4-sulfonyl)-pyrrolidine-2,4-dicarboxylic acid 2-tert-butyl ester 4-methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R,3R,4R,5S)-5-Phenyl-3-((4S,5S)-1,3,4,5-tetraphenyl-imidazolidin-2-yl)-1-(toluene-4-sulfonyl)-pyrrolidine-2,4-dicarboxylic acid 2-tert-butyl ester 4-methyl ester

There total 3 articles about (2R,3R,4R,5S)-5-Phenyl-3-((4S,5S)-1,3,4,5-tetraphenyl-imidazolidin-2-yl)-1-(toluene-4-sulfonyl)-pyrrolidine-2,4-dicarboxylic acid 2-tert-butyl ester 4-methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 135212-33-8
(2R,3R,4R,5S)-5-Phenyl-3-((4R,5R)-1,3,4,5-tetraphenyl-imidazolidin-2-yl)-pyrrolidine-2,4-dicarboxylic acid 2-tert-butyl ester 4-methyl ester

: 98-59-9
p-toluenesulfonyl chloride

: 135075-70-6
(2R,3R,4R,5S)-5-Phenyl-3-((4S,5S)-1,3,4,5-tetraphenyl-imidazolidin-2-yl)-1-(toluene-4-sulfonyl)-pyrrolidine-2,4-dicarboxylic acid 2-tert-butyl ester 4-methyl ester

Guidance literature:: With triethylamine; In chloroform; for 5h; Heating;
DOI:10.1021/jo00014a028

Reference yield:

: 5837-72-9
methyl (E)-4-oxo-2-butenoate

: 135075-70-6
(2R,3R,4R,5S)-5-Phenyl-3-((4S,5S)-1,3,4,5-tetraphenyl-imidazolidin-2-yl)-1-(toluene-4-sulfonyl)-pyrrolidine-2,4-dicarboxylic acid 2-tert-butyl ester 4-methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 88 percent / p-toluenesulfonic acid / CHCl₃ / Heating

2: 1.) butyllithium / 1.) THF, 2.) -78 deg C

3: 80 percent / NEt₃ / CHCl₃ / 5 h / Heating

With n-butyllithium; toluene-4-sulfonic acid; triethylamine; In chloroform;
DOI:10.1021/jo00014a028

Reference yield:

: 35583-19-8
(1R,2R)-trans-N,N',1,2-tetraphenylethane-1,2-diamine

: 135075-70-6
(2R,3R,4R,5S)-5-Phenyl-3-((4S,5S)-1,3,4,5-tetraphenyl-imidazolidin-2-yl)-1-(toluene-4-sulfonyl)-pyrrolidine-2,4-dicarboxylic acid 2-tert-butyl ester 4-methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 88 percent / p-toluenesulfonic acid / CHCl₃ / Heating

2: 1.) butyllithium / 1.) THF, 2.) -78 deg C

3: 80 percent / NEt₃ / CHCl₃ / 5 h / Heating

With n-butyllithium; toluene-4-sulfonic acid; triethylamine; In chloroform;
DOI:10.1021/jo00014a028