Technology Process of C16H25NO6
There total 12 articles about C16H25NO6 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 8 steps
1.1: triethylamine; tetra-(n-butyl)ammonium iodide / N,N-dimethyl-formamide / 36 h / 70 °C / Inert atmosphere
2.1: boron trifluoride diethyl etherate / dichloromethane / 5 h / 0 - 20 °C / Inert atmosphere
2.2: 0.5 h
3.1: dichloromethane / -78 °C / Inert atmosphere
3.2: 2.08 h / -78 °C / Inert atmosphere
3.3: 0.67 h / -78 - 0 °C
4.1: dichloromethane
5.1: oxalyl dichloride; dimethyl sulfoxide
6.1: -78 °C
7.1: water; acetic acid / tetrahydrofuran
8.1: hydrogen / palladium on activated charcoal
With
oxalyl dichloride; boron trifluoride diethyl etherate; water; hydrogen; tetra-(n-butyl)ammonium iodide; acetic acid; dimethyl sulfoxide; triethylamine;
palladium on activated charcoal;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 1H-imidazole / N,N-dimethyl-formamide
2: magnesium / tetrahydrofuran
3: dichloromethane
4: oxalyl dichloride; dimethyl sulfoxide
5: -78 °C
6: water; acetic acid / tetrahydrofuran
7: hydrogen / palladium on activated charcoal
With
1H-imidazole; oxalyl dichloride; water; hydrogen; magnesium; acetic acid; dimethyl sulfoxide;
palladium on activated charcoal;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 9 steps
1.1: pyridine / 1.75 h / 0 - 20 °C / Inert atmosphere
2.1: triethylamine; tetra-(n-butyl)ammonium iodide / N,N-dimethyl-formamide / 36 h / 70 °C / Inert atmosphere
3.1: boron trifluoride diethyl etherate / dichloromethane / 5 h / 0 - 20 °C / Inert atmosphere
3.2: 0.5 h
4.1: dichloromethane / -78 °C / Inert atmosphere
4.2: 2.08 h / -78 °C / Inert atmosphere
4.3: 0.67 h / -78 - 0 °C
5.1: dichloromethane
6.1: oxalyl dichloride; dimethyl sulfoxide
7.1: -78 °C
8.1: water; acetic acid / tetrahydrofuran
9.1: hydrogen / palladium on activated charcoal
With
pyridine; oxalyl dichloride; boron trifluoride diethyl etherate; water; hydrogen; tetra-(n-butyl)ammonium iodide; acetic acid; dimethyl sulfoxide; triethylamine;
palladium on activated charcoal;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;