(R)-2-[(3S,5R)-4-[(2-amino-acetylamino)-acetyl]-3-(3-chloro-phenyl)-5-methyl-2-oxo-[1,4]diazepan-1-yl]-3-naphthalen-1-yl-propionamide trifluoroacetate

Base Information

Chemical Name:(R)-2-[(3S,5R)-4-[(2-amino-acetylamino)-acetyl]-3-(3-chloro-phenyl)-5-methyl-2-oxo-[1,4]diazepan-1-yl]-3-naphthalen-1-yl-propionamide trifluoroacetate
CAS No.:913357-96-7
Molecular Formula:C₂HF₃O₂*C₂₉H₃₂ClN₅O₄
Molecular Weight:664.081
Hs Code.:

Synonyms:(R)-2-[(3S,5R)-4-[(2-amino-acetylamino)-acetyl]-3-(3-chloro-phenyl)-5-methyl-2-oxo-[1,4]diazepan-1-yl]-3-naphthalen-1-yl-propionamide trifluoroacetate

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Chemical Property of (R)-2-[(3S,5R)-4-[(2-amino-acetylamino)-acetyl]-3-(3-chloro-phenyl)-5-methyl-2-oxo-[1,4]diazepan-1-yl]-3-naphthalen-1-yl-propionamide trifluoroacetate

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Technology Process of (R)-2-[(3S,5R)-4-[(2-amino-acetylamino)-acetyl]-3-(3-chloro-phenyl)-5-methyl-2-oxo-[1,4]diazepan-1-yl]-3-naphthalen-1-yl-propionamide trifluoroacetate

There total 1 articles about (R)-2-[(3S,5R)-4-[(2-amino-acetylamino)-acetyl]-3-(3-chloro-phenyl)-5-methyl-2-oxo-[1,4]diazepan-1-yl]-3-naphthalen-1-yl-propionamide trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₇H₂₉ClN₄O₃

: 5694-33-7
N-succinylglycine

: 913357-96-7
(R)-2-[(3S,5R)-4-[(2-amino-acetylamino)-acetyl]-3-(3-chloro-phenyl)-5-methyl-2-oxo-[1,4]diazepan-1-yl]-3-naphthalen-1-yl-propionamide trifluoroacetate

Guidance literature:: With N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In N,N-dimethyl-formamide; for 15h;

Reference yield:

: 913357-96-7
(R)-2-[(3S,5R)-4-[(2-amino-acetylamino)-acetyl]-3-(3-chloro-phenyl)-5-methyl-2-oxo-[1,4]diazepan-1-yl]-3-naphthalen-1-yl-propionamide trifluoroacetate

: 74-88-4
methyl iodide

: 913358-32-4
({2-[(2S,7R)-4-((R)-1-carbamoyl-2-naphthalen-1-yl-ethyl)-2-(3-chloro-phenyl)-7-methyl-3-oxo-[1,4]diazepan-1-yl]-2-oxo-ethylcarbamoyl}-methyl)-trimethyl-ammonium chloride

Guidance literature:: (R)-2-[(3S,5R)-4-[(2-amino-acetylamino)-acetyl]-3-(3-chloro-phenyl)-5-methyl-2-oxo-[1,4]diazepan-1-yl]-3-naphthalen-1-yl-propionamide trifluoroacetate; methyl iodide; With potassium carbonate; In dichloromethane; at 20 ℃;

With hydrogenchloride; In methanol; water;