aeruginol

Base Information

• Chemical Name: aeruginol
• CAS No.: 154037-50-0
• Molecular Formula: C₁₀H₉NO₂S
• Molecular Weight: 207.253
• Mol file: 154037-50-0.mol

Synonyms:Aeruginol

Chemical Property of aeruginol

Chemical Property:

• Vapor Pressure: 6.7E-09mmHg at 25°C
• Boiling Point: 422.3°Cat760mmHg
• PKA: 8.61±0.30(Predicted)
• Flash Point: 209.2°C
• PSA: 81.33000
• Density: 1.414g/cm³
• LogP: 0.69540

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of aeruginol

There total 5 articles about aeruginol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 23.0%

2-(2-hydroxyphenyl)thiazole-4-carboxylic acid (27501-91-3) → aeruginol (154037-50-0)

Guidance literature:

With borane-THF; In tetrahydrofuran;

DOI:10.1021/acsinfecdis.0c00897

Reference yield:

2'-(2-hydroxyphenyl)-2'-thiazole-4'-carboxaldehyde (83053-39-8) → aeruginol (154037-50-0)

Guidance literature:

With sodium tetrahydroborate; In methanol; Ambient temperature;

Reference yield:

salicylamide (65-45-2) → aeruginol (154037-50-0)

Guidance literature:

Multi-step reaction with 4 steps

1: Lawessons reagent / tetrahydrofuran

2: ethanol

3: lithium hydroxide; water

4: borane-THF / tetrahydrofuran

With Lawessons reagent; borane-THF; water; lithium hydroxide; In tetrahydrofuran; ethanol;

DOI:10.1021/acsinfecdis.0c00897

upstream raw materials:

2'-(2-hydroxyphenyl)-2'-thiazole-4'-carboxaldehyde

salicylamide

2-(2-hydroxyphenyl)thiazole-4-carboxylic acid

2-hydroxythiobenzamide

Refernces

• 1、 Cuppels, Diane A.,Stipanovic, Robert D.,Stoessl, Albert,Stothers, J. B.. "The constitution and properties of a pyochelin-zinc complex". . p. 2126 - 2130. Retrieved 2007/10/02.