Droloxifene

Base Information

Chemical Name:Droloxifene
CAS No.:82413-20-5
Molecular Formula:C26H29NO2
Molecular Weight:387.522
Hs Code.:
European Community (EC) Number:428-010-4
UNII:0M67U6Z98F
DSSTox Substance ID:DTXSID9022441
Wikipedia:Droloxifene
Wikidata:Q27116249
NCI Thesaurus Code:C969
Metabolomics Workbench ID:42511
ChEMBL ID:CHEMBL487
Mol file:82413-20-5.mol

Synonyms:3-hydroxytamoxifen;3-hydroxytamoxifen citrate;droloxifene;droloxifene citrate;FK 435;FK-435;FK435;meta-hydroxytamoxifen

Suppliers and Price of Droloxifene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(E)-3-HydroxyTamoxifen
10mg
$ 125.00

Medical Isotopes, Inc.
3-HydroxyTamoxifen
2.5 mg
$ 875.00

Medical Isotopes, Inc.
3-HydroxyTamoxifen
12.5 mg
$ 2000.00

American Custom Chemicals Corporation
DROLOXIFENE 95.00%
25MG
$ 1732.50

American Custom Chemicals Corporation
DROLOXIFENE 95.00%
2.5MG
$ 687.50

Total 43 raw suppliers

Chemical Property of Droloxifene

Chemical Property:

Appearance/Colour:off-White to Pale-Beige Solid
Vapor Pressure:1.05E-11mmHg at 25°C
Melting Point:127-129 °C
Refractive Index:1.596
Boiling Point:526.6 °C at 760 mmHg
Flash Point:272.3 °C
PSA：164.83000
Density:1.092 g/cm³
LogP:4.45320
Storage Temp.:Amber Vial, -20°C Freezer
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:6.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:8
Exact Mass:387.219829168
Heavy Atom Count:29
Complexity:501

Purity/Quality:

99% ^*data from raw suppliers

(E)-3-HydroxyTamoxifen ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(=C(C1=CC=C(C=C1)OCCN(C)C)C2=CC(=CC=C2)O)C3=CC=CC=C3
Isomeric SMILES:CC/C(=C(/C1=CC=C(C=C1)OCCN(C)C)\C2=CC(=CC=C2)O)/C3=CC=CC=C3
Uses A Tamoxifen derivative with antitumor effect on estrogen-dependent breast cancer cells A Tamoxifen (T006000) derivative with antitumor effect on estrogen-dependent breast cancer cells. anti-estrogen, anti-hyperlipoproteinemic, reduces bone loss

Technology Process of Droloxifene

There total 36 articles about Droloxifene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%