Methyl phenyl-piperazin-1-YL-acetate

Base Information

Chemical Name:Methyl phenyl-piperazin-1-YL-acetate
CAS No.:864932-46-7
Molecular Formula:C₁₃H₁₈N₂O₂
Molecular Weight:234.298
Hs Code.:
DSSTox Substance ID:DTXSID20401217

Synonyms:METHYL PHENYL-PIPERAZIN-1-YL-ACETATE;864932-46-7;phenyl-piperazin-1-yl-acetic acid methyl ester;METHYL 2-PHENYL-2-(PIPERAZIN-1-YL)ACETATE;SCHEMBL3624300;DTXSID20401217;YLSZHCRANHDFCD-UHFFFAOYSA-N;AKOS000268836;CS-0346788;EN300-25484

Suppliers and Price of Methyl phenyl-piperazin-1-YL-acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Methyl phenyl-piperazin-1-YL-acetate

Chemical Property:

XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:234.136827821
Heavy Atom Count:17
Complexity:246

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)C(C1=CC=CC=C1)N2CCNCC2

Technology Process of Methyl phenyl-piperazin-1-YL-acetate

There total 5 articles about Methyl phenyl-piperazin-1-YL-acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

: 6591-61-3,24461-61-8,26682-99-5,37760-98-8
(S)-Phenylglycine methyl ester

: 821-48-7
bis-(2-chloroethyl)amine hydrochloride

: 864932-46-7
methyl 2-phenyl-2-(piperazin-1-yl)acetate

Guidance literature:: (S)-Phenylglycine methyl ester; bis-(2-chloroethyl)amine hydrochloride; With triethylamine; In butan-1-ol; at 120 - 130 ℃; for 16h;

With sodium hydroxide; In water; pH=> 7;

Reference yield: 36.0%

: 347186-48-5
tert-butyl 4-(2-methoxy-2-oxo-1-phenylethyl)piperazine-1-carboxylate

: 864932-46-7
methyl 2-phenyl-2-(piperazin-1-yl)acetate

Guidance literature:: tert-butyl 4-(2-methoxy-2-oxo-1-phenylethyl)piperazine-1-carboxylate; With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 18h;

With sodium hydrogencarbonate; In dichloromethane; water;