C₂₀H₁₉Cl₃FN₃O₃

Base Information

Chemical Name:C₂₀H₁₉Cl₃FN₃O₃
CAS No.:1332837-58-7
Molecular Formula:C₂₀H₁₉Cl₃FN₃O₃
Molecular Weight:474.747
Hs Code.:

C<sub>20</sub>H<sub>19</sub>Cl<sub>3</sub>FN<sub>3</sub>O<sub>3</sub>

Synonyms:C₂₀H₁₉Cl₃FN₃O₃

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₂₀H₁₉Cl₃FN₃O₃

Chemical Property:

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Technology Process of C₂₀H₁₉Cl₃FN₃O₃

There total 6 articles about C₂₀H₁₉Cl₃FN₃O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

: 1332837-57-6
C₂₀H₁₇Cl₃FN₃O₅

: 1332837-58-7
C₂₀H₁₉Cl₃FN₃O₃

Guidance literature:: C₂₀H₁₇Cl₃FN₃O₅; With acetic acid; zinc; at 20 ℃; for 16h;

With sodium hydrogencarbonate; In water;

Reference yield:

: 425380-38-7
4-bromo-7-chloro-3a,7a-dihydro-1H-pyrrolo[2,3-c]pyridine

: 1332837-58-7
C₂₀H₁₉Cl₃FN₃O₃

Guidance literature:: Multi-step reaction with 5 steps

1.1: dmap / tetrahydrofuran / 1 h

2.1: bis(pinacol)diborane; potassium acetate / tricyclohexylphosphine; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾ / 1,4-dioxane / 12 h / 80 °C / Inert atmosphere

2.2: 4 h / 0 °C

3.1: toluene-4-sulfonic acid; nickel(II) nitrate hexahydrate / 1 h / Reflux

4.1: triphenylphosphine; di-isopropyl azodicarboxylate / 2 h / 20 °C

5.1: zinc; acetic acid / 16 h / 20 °C

With dmap; nickel(II) nitrate hexahydrate; di-isopropyl azodicarboxylate; potassium acetate; toluene-4-sulfonic acid; acetic acid; triphenylphosphine; bis(pinacol)diborane; zinc; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; tricyclohexylphosphine; In tetrahydrofuran; 1,4-dioxane; 4.1: Mitsunobu reaction;

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 1332837-58-7
C₂₀H₁₉Cl₃FN₃O₃

Guidance literature:: Multi-step reaction with 5 steps

1.1: dmap / tetrahydrofuran / 1 h

2.1: bis(pinacol)diborane; potassium acetate / tricyclohexylphosphine; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾ / 1,4-dioxane / 12 h / 80 °C / Inert atmosphere

2.2: 4 h / 0 °C

3.1: toluene-4-sulfonic acid; nickel(II) nitrate hexahydrate / 1 h / Reflux

4.1: triphenylphosphine; di-isopropyl azodicarboxylate / 2 h / 20 °C

5.1: zinc; acetic acid / 16 h / 20 °C

With dmap; nickel(II) nitrate hexahydrate; di-isopropyl azodicarboxylate; potassium acetate; toluene-4-sulfonic acid; acetic acid; triphenylphosphine; bis(pinacol)diborane; zinc; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; tricyclohexylphosphine; In tetrahydrofuran; 1,4-dioxane; 4.1: Mitsunobu reaction;