1-(4-methoxyphenyl)-2-naphthylacetonitrile

Base Information

• Chemical Name: 1-(4-methoxyphenyl)-2-naphthylacetonitrile
• CAS No.: 1363650-13-8
• Molecular Formula: C₁₉H₁₅NO
• Molecular Weight: 273.334
• Mol file: 1363650-13-8.mol

Synonyms:1-(4-methoxyphenyl)-2-naphthylacetonitrile

Chemical Property of 1-(4-methoxyphenyl)-2-naphthylacetonitrile

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 1-(4-methoxyphenyl)-2-naphthylacetonitrile

There total 2 articles about 1-(4-methoxyphenyl)-2-naphthylacetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-naphthaleneacetonitrile (7498-57-9) + para-iodoanisole (696-62-8) → 2-(4-methoxyphenyl)-2-(naphthalen-2-yl)acetonitrile (186523-28-4) + 1-(4-methoxyphenyl)-2-naphthylacetonitrile (1363650-13-8) + methoxybenzene (100-66-3)

Guidance literature:

2-naphthaleneacetonitrile; With potassium tert-butylate; In dimethyl sulfoxide; for 0.25h; Inert atmosphere;

para-iodoanisole; In dimethyl sulfoxide; for 3h; regioselective reaction; Irradiation; Inert atmosphere;

DOI:10.1039/c1nj20699k

Reference yield:

2-naphthaleneacetonitrile (7498-57-9) + para-iodoanisole (696-62-8) → 2-(4-methoxyphenyl)-2-(naphthalen-2-yl)acetonitrile (186523-28-4) + 1-(4-methoxyphenyl)-2-naphthylacetonitrile (1363650-13-8)

Guidance literature:

2-naphthaleneacetonitrile; With potassium tert-butylate; In dimethyl sulfoxide; for 0.25h; Inert atmosphere;

para-iodoanisole; In dimethyl sulfoxide; for 3h; regioselective reaction; Irradiation; Inert atmosphere;

DOI:10.1039/c1nj20699k

upstream raw materials:

2-naphthaleneacetonitrile

para-iodoanisole