(1S,3R)-3-(4-methoxyphenyl)cyclopentyl 4-(trifluoromethyl)benzenesulfonate

Base Information

Chemical Name:(1S,3R)-3-(4-methoxyphenyl)cyclopentyl 4-(trifluoromethyl)benzenesulfonate
CAS No.:1325231-60-4
Molecular Formula:C₁₉H₁₉F₃O₄S
Molecular Weight:400.419
Hs Code.:

Synonyms:(1S,3R)-3-(4-methoxyphenyl)cyclopentyl 4-(trifluoromethyl)benzenesulfonate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (1S,3R)-3-(4-methoxyphenyl)cyclopentyl 4-(trifluoromethyl)benzenesulfonate

Chemical Property:

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Technology Process of (1S,3R)-3-(4-methoxyphenyl)cyclopentyl 4-(trifluoromethyl)benzenesulfonate

There total 3 articles about (1S,3R)-3-(4-methoxyphenyl)cyclopentyl 4-(trifluoromethyl)benzenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2991-42-6
4-trifluorophenylsulfonyl chloride

: 1325231-59-1
(1S,3R)-3-(4-methoxyphenyl)cyclopentanol

: 1325231-60-4
(1S,3R)-3-(4-methoxyphenyl)cyclopentyl 4-(trifluoromethyl)benzenesulfonate

Guidance literature:: With dmap; triethylamine; In dichloromethane; at 0 - 20 ℃;

Reference yield:

: 155325-51-2
(R)-3-(4-methoxyphenyl)cyclopentan-1-one

: 1325231-60-4
(1S,3R)-3-(4-methoxyphenyl)cyclopentyl 4-(trifluoromethyl)benzenesulfonate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium formate; NAD; formate hydrogenase 101; ketoreductase NAD dependent 102 / 30 °C / pH 6.5 / Aqueous phosphate buffer; Enzymatic reaction

2: dmap; triethylamine / dichloromethane / 0 - 20 °C

With dmap; formate hydrogenase 101; ketoreductase NAD dependent 102; NAD; sodium formate; triethylamine; In dichloromethane;

Reference yield:

: 930-30-3
cyclopent-2-enone

: 1325231-60-4
(1S,3R)-3-(4-methoxyphenyl)cyclopentyl 4-(trifluoromethyl)benzenesulfonate

Guidance literature:: Multi-step reaction with 3 steps

1: water; (R)-2,2'-bis(diphenylphosphanyl)-1,1'-binaphthyl / 1,4-dioxane / 100 °C

2: sodium formate; NAD; formate hydrogenase 101; ketoreductase NAD dependent 102 / 30 °C / pH 6.5 / Aqueous phosphate buffer; Enzymatic reaction

3: dmap; triethylamine / dichloromethane / 0 - 20 °C

With dmap; formate hydrogenase 101; ketoreductase NAD dependent 102; NAD; water; sodium formate; (R)-2,2'-bis(diphenylphosphanyl)-1,1'-binaphthyl; triethylamine; In 1,4-dioxane; dichloromethane;