Sodium nitroprusside anhydrous

Base Information

• Chemical Name: Sodium nitroprusside anhydrous
• CAS No.: 14402-89-2
• Molecular Formula: C5Fe N6 O . 2 Na
• Molecular Weight: 261.94
• European Community (EC) Number: 238-373-9
• Mol file: 14402-89-2.mol

Synonyms:14402-89-2;Sodium nitroprusside anhydrous;disodium;iron(3+);nitroxyl anion;pentacyanide;iron(4+);Nitroprusside (disodium dihydrate);Ro 21-2498;Sodium nitroprusside dihydrate;Sodium Nitroferricyanide(III) Dihydrate;C5FeN6O.2Na;Sodium nitroprussate;Nitroprusside (Sodium);C5FeN6O.2H2O.2Na;Nitroprussidnatrium [German];Na2[Fe(CN)5(NO)];Sodium nitrosylpentacyanoferrate;CCRIS 1912;SCHEMBL3020702;Sodium Nitroprusside (anhydrous);CHEBI:29321;Disodium nitrosylpentacyanoferrate;Disodium pentacyanonitrosylferrate;disodium pentacyanidonitrosylferrate;HMS2091E13;AMY22414;HY-B0564;EINECS 238-373-9;AKOS037515480;Sodium nitrosylpentacyanoferrate (III);sodium pentacyanidonitrosylferrate(2-);CCG-212464;sodium pentacyanidonitrosylferrate(III);Nitroprusside, Disodium Salt, Dihydrate;LS-68783;LS-68784;S4059;SR-05000001550;FERRATE(2-), PENTACYANONITROSYL-, DISODIUM;SR-05000001550-1;Ferrate(2-), pentakis(cyano-kappaC)nitrosyl-, disodium, (OC-6-22)-

Chemical Property of Sodium nitroprusside anhydrous

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 148.38000
• Density: g/cm³
• LogP: 0.29850
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 12
• Rotatable Bond Count: 0
• Exact Mass: 261.927833
• Heavy Atom Count: 15
• Complexity: 119

Purity/Quality:

Sodium nitroprusside United States Pharmacopeia (USP) Reference Standard ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T
• Statements: 25
• Safety Statements: 45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: [C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[N-]=O.[Na+].[Na+].[Fe+4]
• Description: Sodium nitroprusside is a powerful, instantaneous-acting intravenous drug used to lower blood pressure in hypertensive crises. The hypotensive effect is caused by peripheral vasodilation resulting from a direct effect on both arterial and venous vessels.
• Uses: Sodium Nitroprusside is a potent vasodilator working through releasing NO spontaneously in blood
• Biological Functions: Sodium nitroprusside (Nipride) is a potent directly acting vasodilator capable of reducing blood pressure in all patients, regardless of the cause of hypertension. It is used only by the intravenous route for the treatment of hypertensive emergencies. The pharmacological activity is caused by the nitroso moiety. The actions of the drug are similar to those of the nitrites and nitrates that are used as antianginal agents. The action of the nitrovasodilators depends on the intracellular production of cGMP.
• Clinical Use: Sodium nitroprusside is used in the management of hypertensive crisis. Although it is effective in every form of hypertension because of its relatively favorable effect on cardiac performance, sodium nitroprusside has special importance in the treatment of severe hypertension with acute myocardial infarction or left ventricular failure. Because the drug reduces preload (by venodilation) and afterload (by arteriolar dilation), it improves ventricular performance and in fact is sometimes used in patients with refractory heart failure, even in the absence of hypertension.
• Drug interactions: Potentially hazardous interactions with other drugs Anaesthetics: enhanced hypotensive effect.