di-tert-butyl 1,2-bis(2-phenylethyl)hydrazine-1,2-dicarboxylate

Base Information

• Chemical Name: di-tert-butyl 1,2-bis(2-phenylethyl)hydrazine-1,2-dicarboxylate
• CAS No.: 1453190-44-7
• Molecular Formula: C₂₆H₃₆N₂O₄
• Molecular Weight: 440.583
• Mol file: 1453190-44-7.mol

Synonyms:di-tert-butyl 1,2-bis(2-phenylethyl)hydrazine-1,2-dicarboxylate

Chemical Property of di-tert-butyl 1,2-bis(2-phenylethyl)hydrazine-1,2-dicarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of di-tert-butyl 1,2-bis(2-phenylethyl)hydrazine-1,2-dicarboxylate

There total 1 articles about di-tert-butyl 1,2-bis(2-phenylethyl)hydrazine-1,2-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

1,2-bis(t-butyloxycarbonyl)hydrazine (16466-61-8) + 1-phenyl-2-bromoethane (103-63-9) → di-tert-butyl 1,2-bis(2-phenylethyl)hydrazine-1,2-dicarboxylate (1453190-44-7)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 2.5h; Cooling with ice; Inert atmosphere;

DOI:10.1016/j.tetlet.2013.07.134

Reference yield:

di-tert-butyl 1,2-bis(2-phenylethyl)hydrazine-1,2-dicarboxylate (1453190-44-7) → C16H20N2*ClH (98468-21-4)

Guidance literature:

With methanol; acetyl chloride; at 0 - 20 ℃; for 18h; Cooling with ice;

DOI:10.1016/j.tetlet.2013.07.134

Reference yield:

di-tert-butyl 1,2-bis(2-phenylethyl)hydrazine-1,2-dicarboxylate (1453190-44-7) → C40H40N2O8

Guidance literature:

Multi-step reaction with 2 steps

1: acetyl chloride; methanol / 18 h / 0 - 20 °C / Cooling with ice

2: N-ethyl-N,N-diisopropylamine / dichloromethane / 1.5 h / 0 - 20 °C

With methanol; N-ethyl-N,N-diisopropylamine; acetyl chloride; In dichloromethane;

DOI:10.1016/j.tetlet.2013.07.134

upstream raw materials:

1,2-bis(t-butyloxycarbonyl)hydrazine

1-phenyl-2-bromoethane

Downstream raw materials:

C₁₆H₂₀N₂*ClH

(E)-3-(4-hydroxy-3-methoxyphenyl)-N'-((E)-3-(4-hydroxy-3-methoxyphenyl)acryloyl)-N,N'-diphenethylacrylohydrazide