2-(3,4-dichlorophenyl)-2-methyl-4-[4-(2-oxopyrrolidin-1-yl)piperidin-1-yl]butyric acid

Base Information

• Chemical Name: 2-(3,4-dichlorophenyl)-2-methyl-4-[4-(2-oxopyrrolidin-1-yl)piperidin-1-yl]butyric acid
• CAS No.: 1131739-56-4
• Molecular Formula: C₂₀H₂₆Cl₂N₂O₃
• Molecular Weight: 413.344

Synonyms:2-(3,4-dichlorophenyl)-2-methyl-4-[4-(2-oxopyrrolidin-1-yl)piperidin-1-yl]butyric acid

Chemical Property of 2-(3,4-dichlorophenyl)-2-methyl-4-[4-(2-oxopyrrolidin-1-yl)piperidin-1-yl]butyric acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(3,4-dichlorophenyl)-2-methyl-4-[4-(2-oxopyrrolidin-1-yl)piperidin-1-yl]butyric acid

There total 1 articles about 2-(3,4-dichlorophenyl)-2-methyl-4-[4-(2-oxopyrrolidin-1-yl)piperidin-1-yl]butyric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(3,4-dichlorophenyl)-2-methyl-4-[4-(2-oxopyrrolidin-1-yl)piperidin-1-yl]butyric acid methyl ester (1131739-58-6) → 2-(3,4-dichlorophenyl)-2-methyl-4-[4-(2-oxopyrrolidin-1-yl)piperidin-1-yl]butyric acid (1131739-56-4)

Guidance literature:

With lithium hydroxide monohydrate; water; In tetrahydrofuran; at 20 ℃; for 67h;

DOI:10.1021/jm900948q

Reference yield: 69.0%

(3-fluoro-4-(trifluoromethyl)benzyl)methylamine, hydrochloride (1131739-64-4) + 2-(3,4-dichlorophenyl)-2-methyl-4-[4-(2-oxopyrrolidin-1-yl)piperidin-1-yl]butyric acid (1131739-56-4) → 2-(3,4-dichlorophenyl)-N-(4-fluoro-3-(trifluoromethyl)benzyl)-2,N-dimethyl-4-[4-(2-oxopyrrolidin-1-yl)piperidin-1-yl]butyramide (1131738-29-8)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; HATU; In N,N-dimethyl-formamide; at 20 ℃; for 42h;

DOI:10.1021/jm900948q

Reference yield: 59.0%

2-(3,4-dichlorophenyl)-2-methyl-4-[4-(2-oxopyrrolidin-1-yl)piperidin-1-yl]butyric acid (1131739-56-4) + 1-(4-fluoro-3-trifluoromethyl-phenyl)-ethyl(methyl)amine hydrochloride (1131739-80-4) → C29H33Cl2F4N3O2

Guidance literature:

With N-ethyl-N,N-diisopropylamine; HATU; In N,N-dimethyl-formamide; at 20 ℃;

upstream raw materials:

2-(3,4-dichlorophenyl)-2-methyl-4-[4-(2-oxopyrrolidin-1-yl)piperidin-1-yl]butyric acid methyl ester

Downstream raw materials:

2-(3,4-dichlorophenyl)-N-(4-fluoro-3-(trifluoromethyl)benzyl)-2,N-dimethyl-4-[4-(2-oxopyrrolidin-1-yl)piperidin-1-yl]butyramide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1131739-56-4 2-(3,4-dichlorophenyl)-2-methyl-4-[4-(2-oxopyrrolidin-1-yl)piperidin-1-yl]butyric acid

Send

Send

Metric Ton KG G Pound L ML

Send

Send