5,7-Dichlorokynurenic acid

Base Information

Chemical Name:5,7-Dichlorokynurenic acid
CAS No.:131123-76-7
Molecular Formula:C₁₀H₅Cl₂NO₃
Molecular Weight:258.061
Hs Code.:2933499090
European Community (EC) Number:633-778-0
UNII:T61ORK73PY
DSSTox Substance ID:DTXSID80893710
Nikkaji Number:J362.160J,J377.344B
Wikipedia:5,7-Dichlorokynurenic_acid
Wikidata:Q5204515
Pharos Ligand ID:C87NR74T85NA
Metabolomics Workbench ID:146547
ChEMBL ID:CHEMBL50267
Mol file:131123-76-7.mol

Synonyms:5,7-DCKA;5,7-dichlorokynurenic acid;5,7-dichloroquinurenic acid

Suppliers and Price of 5,7-Dichlorokynurenic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
5,7-Dichlorokynurenic acid sodium salt
10mg
$ 339.00

Usbiological
5,7-Dichlorokynurenic acid
10mg
$ 339.00

Tocris
5,7-Dichlorokynurenic acid sodium salt ≥98%(HPLC)
50
$ 424.00

Tocris
5,7-Dichlorokynurenicacid ≥98%(HPLC)
50
$ 396.00

Tocris
5,7-Dichlorokynurenicacid ≥98%(HPLC)
10
$ 103.00

Tocris
5,7-Dichlorokynurenic acid sodium salt ≥98%(HPLC)
10
$ 101.00

Crysdot
5,7-Dichloro-4-hydroxyquinoline-2-carboxylicacid 95+%
1g
$ 333.00

Crysdot
5,7-Dichloro-4-hydroxyquinoline-2-carboxylicacid 95+%
5g
$ 931.00

Chemenu
5,7-Dichloro-4-hydroxyquinoline-2-carboxylicacid 95%
5g
$ 870.00

Chemenu
5,7-Dichloro-4-hydroxyquinoline-2-carboxylicacid 95%
1g
$ 311.00

Total 15 raw suppliers

Chemical Property of 5,7-Dichlorokynurenic acid

Chemical Property:

Vapor Pressure:4.26E-08mmHg at 25°C
Refractive Index:1.656
Boiling Point:428.3 °C at 760 mmHg
Flash Point:212.8 °C
PSA：70.42000
Density:1.651g/cm³
LogP:2.94540
Storage Temp.:Desiccate at RT
Solubility.:0.1 M NaOH: soluble
XLogP3:2.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:256.9646484
Heavy Atom Count:16
Complexity:369

Purity/Quality:

99% ^*data from raw suppliers

5,7-Dichlorokynurenic acid sodium salt ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C=C(C2=C1NC(=CC2=O)C(=O)O)Cl)Cl
Uses 5,7-Dichlorokynurenic acid is a potent NMDA receptor glycine binding site antagonist.

Technology Process of 5,7-Dichlorokynurenic acid

There total 3 articles about 5,7-Dichlorokynurenic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 157848-08-3,166981-79-9
5,7-dichloro-4-hydroxy-quinoline-2-carboxylic acid ethyl ester

: 131123-76-7
5,7-dichlorokynurenic acid

Guidance literature:: With sodium hydroxide;
DOI:10.1021/ja01211a030

Reference yield:

: 626-43-7
3,5-Dichloroaniline

: 131123-76-7
5,7-dichlorokynurenic acid

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid / Erhitzen des Reaktionsprodukts in Mineraloel auf 250grad

2: aqueous NaOH

With sodium hydroxide; acetic acid;
DOI:10.1021/ja01211a030