((4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-diyl)bis(bis(4-(tert-butyl)phenyl)methanol)

Base Information

• Chemical Name: ((4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-diyl)bis(bis(4-(tert-butyl)phenyl)methanol)
• CAS No.: 163726-72-5
• Molecular Formula: C₄₇H₆₂O₄
• Molecular Weight: 691.007

Synonyms:((4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-diyl)bis(bis(4-(tert-butyl)phenyl)methanol)

Chemical Property of ((4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-diyl)bis(bis(4-(tert-butyl)phenyl)methanol)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ((4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-diyl)bis(bis(4-(tert-butyl)phenyl)methanol)

There total 3 articles about ((4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-diyl)bis(bis(4-(tert-butyl)phenyl)methanol) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

(-)-dimethy-2,3-O-isopropylidene-L-tartrate (37031-29-1) + 1-bromo-4-tert-butylbenzene (3972-65-4) → ((4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-diyl)bis(bis(4-(tert-butyl)phenyl)methanol) (163726-72-5)

Guidance literature:

1-bromo-4-tert-butylbenzene; With iodine; magnesium; In tetrahydrofuran; at 80 ℃; for 2h; Inert atmosphere;

(-)-dimethy-2,3-O-isopropylidene-L-tartrate; In tetrahydrofuran; for 12h; Reflux; Inert atmosphere;

DOI:10.1021/ja500029w

Reference yield: 51.0%

diethyl (4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-dicarboxylate (59779-75-8) + 4-tert-butylmagnesium bromide (63488-10-8) → ((4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-diyl)bis(bis(4-(tert-butyl)phenyl)methanol) (163726-72-5)

Guidance literature:

In tetrahydrofuran; Schlenk technique; Reflux; Inert atmosphere;

DOI:10.1002/chem.201500352

Reference yield:

(-)-dimethy-2,3-O-isopropylidene-L-tartrate (37031-29-1) + 4-tert-butylmagnesium bromide (63488-10-8) → ((4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-diyl)bis(bis(4-(tert-butyl)phenyl)methanol) (163726-72-5)

Guidance literature:

In tetrahydrofuran;

DOI:10.1021/acs.orglett.9b04374

upstream raw materials:

(-)-dimethy-2,3-O-isopropylidene-L-tartrate

1-bromo-4-tert-butylbenzene

diethyl (4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-dicarboxylate

4-tert-butylmagnesium bromide

Downstream raw materials:

C₄₇H₆₀ClO₄P

(4-tert-butylphenyl-TADDOL)PN(Me)Ph

C₄₉H₆₆NO₄P

Br^(1-)*C₅₃H₇₂NO₂⁽¹⁺⁾

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 163726-72-5 ((4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-diyl)bis(bis(4-(tert-butyl)phenyl)methanol)

Send

Send

Metric Ton KG G Pound L ML

Send

Send