59779-75-8Relevant articles and documents
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Tsuzuki
, p. 255 (1935)
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Design, synthesis and evaluation of 2,2-dimethyl-1,3-dioxolane derivatives as human rhinovirus 3C protease inhibitors
Zhang, Qiyan,Cao, Ruiyuan,Liu, An,Lei, Shihai,Li, Yuexiang,Yang, Jingjing,Li, Song,Xiao, Junhai
, p. 4061 - 4065 (2017)
The human rhinovirus (HRV) is the most significant cause of the common cold all over the world. The maturation and replication of this virus entirely depend on the activity of a virus-encoded 3C protease. Due to the high conservation among different serot
A Synthesis Strategy for the Production of a Macrolactone of Gulmirecin A via a Ni(0)-Mediated Reductive Cyclization Reaction
Ichikawa, Satoshi,Katsuyama, Akira,Kitahata, Shun
supporting information, (2020/03/30)
A synthesis strategy for the production of a key synthetic intermediate of gulmirecin A was described. The key reaction in the preparation of the 12-membered macrolactone is the Ni(0)-mediated reductive cyclization reaction of ynal using an N-heterocyclic carbene ligand and silane reductant. In addition, the α-selective glycosylation reaction of the macrolactone was performed to demonstrate the synthesis of gulmirecin and disciformycin precursors.
2,2-dimethyl-1,2-dioxolame derivative, preparation method and application thereof
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Paragraph 0119-0120, (2019/01/23)
The invention relates to a compound shown in formula I, a despinner or optical isomer thereof, pharmacologically acceptable salt, solvate and hydrate thereof, pharmaceutical composition containing thecompound, and application of the compound in preparatio