cholest-6-en-3-yl 4-[(E)-(4-methoxyphenyl)diazenyl]benzoate

Base Information

• Chemical Name: cholest-6-en-3-yl 4-[(E)-(4-methoxyphenyl)diazenyl]benzoate
• CAS No.: 139879-15-5
• Molecular Formula: C₄₁H₅₆N₂O₃
• Molecular Weight: 624.907
• Mol file: 139879-15-5.mol

Synonyms:cholest-6-en-3-yl 4-[(E)-(4-methoxyphenyl)diazenyl]benzoate

Chemical Property of cholest-6-en-3-yl 4-[(E)-(4-methoxyphenyl)diazenyl]benzoate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of cholest-6-en-3-yl 4-[(E)-(4-methoxyphenyl)diazenyl]benzoate

There total 3 articles about cholest-6-en-3-yl 4-[(E)-(4-methoxyphenyl)diazenyl]benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

(E)-1-{4-[(4-methoxyphenyl)diazenyl]benzoyl}-1H-benzotriazole (1174181-88-4) + cholesterol (57-88-5) → cholest-6-en-3-yl 4-[(E)-(4-methoxyphenyl)diazenyl]benzoate (139879-15-5)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; at 20 ℃; for 12h;

DOI:10.1055/s-0029-1216786

Reference yield: 48.0%

cholesterol (57-88-5) + (E)-4-((4-methoxyphenyl)diazenyl)benzoic acid (174023-08-6) → cholest-6-en-3-yl 4-[(E)-(4-methoxyphenyl)diazenyl]benzoate (139879-15-5)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; for 4h; Ambient temperature;

DOI:10.1021/ja00094a023

Reference yield:

4-(4-hydroxyphenylazo)benzoic acid (105299-45-4) → cholest-6-en-3-yl 4-[(E)-(4-methoxyphenyl)diazenyl]benzoate (139879-15-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 35 percent / K₂CO₃ / dimethylformamide / 16 h / Heating

2: 48 percent / 4-(dimethylamino)pyridine, dicyclohexylcarbodiimide / CH₂Cl₂ / 4 h / Ambient temperature

With dmap; potassium carbonate; dicyclohexyl-carbodiimide; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/ja00094a023

upstream raw materials:

cholesterol

(E)-4-((4-methoxyphenyl)diazenyl)benzoic acid

4-(4-hydroxyphenylazo)benzoic acid

(E)-1-{4-[(4-methoxyphenyl)diazenyl]benzoyl}-1H-benzotriazole

Downstream raw materials:

cis-4-methoxy-4'-((cholesteryloxy)carbonyl)azobenzene