4,5-bis[4-[[(2S)-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]propyl]amino]phenyl]-2-oxazoleacetic acid

Base Information

Chemical Name:4,5-bis[4-[[(2S)-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]propyl]amino]phenyl]-2-oxazoleacetic acid
CAS No.:1313743-11-1
Molecular Formula:C₃₉H₃₇N₅O₉
Molecular Weight:719.751
Hs Code.:

Synonyms:4,5-bis[4-[[(2S)-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]propyl]amino]phenyl]-2-oxazoleacetic acid

Suppliers and Price of 4,5-bis[4-[[(2S)-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]propyl]amino]phenyl]-2-oxazoleacetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4,5-bis[4-[[(2S)-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]propyl]amino]phenyl]-2-oxazoleacetic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4,5-bis[4-[[(2S)-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]propyl]amino]phenyl]-2-oxazoleacetic acid

There total 5 articles about 4,5-bis[4-[[(2S)-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]propyl]amino]phenyl]-2-oxazoleacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 1313743-13-3
4,5-bis[4-[[(2S)-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]propyl]amino]phenyl]-2-oxazoleacetic acid ethyl ester

: 1313743-11-1
4,5-bis[4-[[(2S)-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]propyl]amino]phenyl]-2-oxazoleacetic acid

Guidance literature:: 4,5-bis[4-[[(2S)-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]propyl]amino]phenyl]-2-oxazoleacetic acid ethyl ester; With water; lithium hydroxide; In tetrahydrofuran; at 20 ℃; for 3h;

In water; pH=4;

Reference yield:

: 119-53-9,579-44-2
2-hydroxy-2-phenylacetophenone

: 1313743-11-1
4,5-bis[4-[[(2S)-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]propyl]amino]phenyl]-2-oxazoleacetic acid

Guidance literature:: Multi-step reaction with 5 steps

1.1: dmap; pyridine / dichloromethane / 2.5 h / 10 - 20 °C

1.2: 2 h / Reflux

2.1: nitric acid / 1.5 h / 0 - 20 °C

3.1: hydrogen / 20 % Pd(OH)2/C / ethyl acetate; methanol / 20 °C / 760.05 Torr

4.1: N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline / dichloromethane / 15 h / 20 °C

5.1: water; lithium hydroxide / tetrahydrofuran / 3 h / 20 °C

5.2: pH 4

With pyridine; dmap; water; hydrogen; nitric acid; N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; lithium hydroxide; 20 % Pd(OH)2/C; In tetrahydrofuran; methanol; dichloromethane; ethyl acetate;

Reference yield:

: 26820-93-9
ethyl 4,5-diphenyl-2-oxazoleacetate

: 1313743-11-1
4,5-bis[4-[[(2S)-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]propyl]amino]phenyl]-2-oxazoleacetic acid

Guidance literature:: Multi-step reaction with 4 steps

1.1: nitric acid / 1.5 h / 0 - 20 °C

2.1: hydrogen / 20 % Pd(OH)2/C / ethyl acetate; methanol / 20 °C / 760.05 Torr

3.1: N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline / dichloromethane / 15 h / 20 °C

4.1: water; lithium hydroxide / tetrahydrofuran / 3 h / 20 °C

4.2: pH 4

With water; hydrogen; nitric acid; N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; lithium hydroxide; 20 % Pd(OH)2/C; In tetrahydrofuran; methanol; dichloromethane; ethyl acetate;