4,5-bis[4-[[(2S)-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]propyl]amino]phenyl]-2-oxazoleacetic acid ethyl ester

Base Information

Chemical Name:4,5-bis[4-[[(2S)-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]propyl]amino]phenyl]-2-oxazoleacetic acid ethyl ester
CAS No.:1313743-13-3
Molecular Formula:C₄₁H₄₁N₅O₉
Molecular Weight:747.805
Hs Code.:

Synonyms:4,5-bis[4-[[(2S)-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]propyl]amino]phenyl]-2-oxazoleacetic acid ethyl ester

Suppliers and Price of 4,5-bis[4-[[(2S)-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]propyl]amino]phenyl]-2-oxazoleacetic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4,5-bis[4-[[(2S)-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]propyl]amino]phenyl]-2-oxazoleacetic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4,5-bis[4-[[(2S)-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]propyl]amino]phenyl]-2-oxazoleacetic acid ethyl ester

There total 5 articles about 4,5-bis[4-[[(2S)-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]propyl]amino]phenyl]-2-oxazoleacetic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 1142-20-7
N-Cbz-Ala

: 1313750-85-4
C₁₉H₁₉N₃O₃

: 1313743-13-3
4,5-bis[4-[[(2S)-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]propyl]amino]phenyl]-2-oxazoleacetic acid ethyl ester

Guidance literature:: With N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; In dichloromethane; at 20 ℃; for 15h;

Reference yield:

: 119-53-9,579-44-2
2-hydroxy-2-phenylacetophenone

: 1313743-13-3
4,5-bis[4-[[(2S)-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]propyl]amino]phenyl]-2-oxazoleacetic acid ethyl ester

Guidance literature:: Multi-step reaction with 4 steps

1.1: dmap; pyridine / dichloromethane / 2.5 h / 10 - 20 °C

1.2: 2 h / Reflux

2.1: nitric acid / 1.5 h / 0 - 20 °C

3.1: hydrogen / 20 % Pd(OH)2/C / ethyl acetate; methanol / 20 °C / 760.05 Torr

4.1: N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline / dichloromethane / 15 h / 20 °C

With pyridine; dmap; hydrogen; nitric acid; N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; 20 % Pd(OH)2/C; In methanol; dichloromethane; ethyl acetate;

Reference yield:

: 1313750-84-3
C₁₉H₁₅N₃O₇

: 1313743-13-3
4,5-bis[4-[[(2S)-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]propyl]amino]phenyl]-2-oxazoleacetic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogen / 20 % Pd(OH)2/C / ethyl acetate; methanol / 20 °C / 760.05 Torr

2: N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline / dichloromethane / 15 h / 20 °C

With hydrogen; N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; 20 % Pd(OH)2/C; In methanol; dichloromethane; ethyl acetate;