10-(2-chlorobenzyl)-2-(2-chlorophenyl)-2,3,8,9,10,11-hexahydro-1H-pyrazolo[4',3':3,4]pyrido[1,2-a][1,4]diazepine-1,5(7H)-dione hydrochloride

Base Information

Chemical Name:10-(2-chlorobenzyl)-2-(2-chlorophenyl)-2,3,8,9,10,11-hexahydro-1H-pyrazolo[4',3':3,4]pyrido[1,2-a][1,4]diazepine-1,5(7H)-dione hydrochloride
CAS No.:1350522-75-6
Molecular Formula:C₂₃H₂₀Cl₂N₄O₂*ClH
Molecular Weight:491.804
Hs Code.:

Synonyms:10-(2-chlorobenzyl)-2-(2-chlorophenyl)-2,3,8,9,10,11-hexahydro-1H-pyrazolo[4',3':3,4]pyrido[1,2-a][1,4]diazepine-1,5(7H)-dione hydrochloride

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Chemical Property of 10-(2-chlorobenzyl)-2-(2-chlorophenyl)-2,3,8,9,10,11-hexahydro-1H-pyrazolo[4',3':3,4]pyrido[1,2-a][1,4]diazepine-1,5(7H)-dione hydrochloride

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Technology Process of 10-(2-chlorobenzyl)-2-(2-chlorophenyl)-2,3,8,9,10,11-hexahydro-1H-pyrazolo[4',3':3,4]pyrido[1,2-a][1,4]diazepine-1,5(7H)-dione hydrochloride

There total 2 articles about 10-(2-chlorobenzyl)-2-(2-chlorophenyl)-2,3,8,9,10,11-hexahydro-1H-pyrazolo[4',3':3,4]pyrido[1,2-a][1,4]diazepine-1,5(7H)-dione hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₄H₂₄Cl₂N₄O₃

: 1350522-75-6
10-(2-chlorobenzyl)-2-(2-chlorophenyl)-2,3,8,9,10,11-hexahydro-1H-pyrazolo[4',3':3,4]pyrido[1,2-a][1,4]diazepine-1,5(7H)-dione hydrochloride

Guidance literature:: C₂₄H₂₄Cl₂N₄O₃; With sodium methylate; In methanol; at 20 ℃; for 1h; Inert atmosphere;

With hydrogenchloride; In methanol;
DOI:10.1016/j.bmc.2011.10.016

Reference yield:

: 1350522-88-1
methyl [4-(chloroacetyl)-1-(2-chlorophenyl)-5-hydroxy-1H-pyrazol-3-yl]acetate

: N¹-(2-chlorobenzyl)propane-1,3-diamine

: 1350522-75-6
10-(2-chlorobenzyl)-2-(2-chlorophenyl)-2,3,8,9,10,11-hexahydro-1H-pyrazolo[4',3':3,4]pyrido[1,2-a][1,4]diazepine-1,5(7H)-dione hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1.1: acetonitrile / 3 h / 0 °C / Inert atmosphere

1.2: 1 h / 20 °C / Inert atmosphere

2.1: sodium methylate / methanol / 1 h / 20 °C / Inert atmosphere

With sodium methylate; In methanol; acetonitrile;
DOI:10.1016/j.bmc.2011.10.016