(2R,4aR,6S,6aS,7S,9R,9aS,9bS)-6-Methoxy-2-phenyl-9a-propionyl-octahydro-cyclopenta[4,5]pyrano[3,2-d][1,3]dioxine-7,9-dicarbaldehyde

Base Information

• Chemical Name: (2R,4aR,6S,6aS,7S,9R,9aS,9bS)-6-Methoxy-2-phenyl-9a-propionyl-octahydro-cyclopenta[4,5]pyrano[3,2-d][1,3]dioxine-7,9-dicarbaldehyde
• CAS No.: 201025-02-7
• Molecular Formula: C₂₂H₂₆O₇
• Molecular Weight: 402.444
• Mol file: 201025-02-7.mol

Synonyms:(2R,4aR,6S,6aS,7S,9R,9aS,9bS)-6-Methoxy-2-phenyl-9a-propionyl-octahydro-cyclopenta[4,5]pyrano[3,2-d][1,3]dioxine-7,9-dicarbaldehyde

Chemical Property of (2R,4aR,6S,6aS,7S,9R,9aS,9bS)-6-Methoxy-2-phenyl-9a-propionyl-octahydro-cyclopenta[4,5]pyrano[3,2-d][1,3]dioxine-7,9-dicarbaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2R,4aR,6S,6aS,7S,9R,9aS,9bS)-6-Methoxy-2-phenyl-9a-propionyl-octahydro-cyclopenta[4,5]pyrano[3,2-d][1,3]dioxine-7,9-dicarbaldehyde

There total 1 articles about (2R,4aR,6S,6aS,7S,9R,9aS,9bS)-6-Methoxy-2-phenyl-9a-propionyl-octahydro-cyclopenta[4,5]pyrano[3,2-d][1,3]dioxine-7,9-dicarbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(1S,2S,3S,5R,8R,10S,11S,12R)-10-methoxy-5-phenyl-2-(1-oxopropyl)-4,6,9-trioxatetracyclo[10.2.1.02,11.03,8]pentadec-13-ene (201025-01-6) → (2R,4aR,6S,6aS,7S,9R,9aS,9bS)-6-Methoxy-2-phenyl-9a-propionyl-octahydro-cyclopenta[4,5]pyrano[3,2-d][1,3]dioxine-7,9-dicarbaldehyde (201025-02-7)

Guidance literature:

With dimethylsulfide; ozone; Yield given. Multistep reaction; 1.) CH₂Cl₂, -78 deg C, 2.) CH₂Cl₂, -78 deg C to room temp. 20 min;

DOI:10.1016/S0040-4039(97)10370-7

Reference yield:

(2R,4aR,6S,6aS,7S,9R,9aS,9bS)-6-Methoxy-2-phenyl-9a-propionyl-octahydro-cyclopenta[4,5]pyrano[3,2-d][1,3]dioxine-7,9-dicarbaldehyde (201025-02-7) → (2R,2aS,3S,4aR,7R,8aS,8bS,11aR)-3-Methoxy-10-methyl-9-oxo-7-phenyl-1,2,2a,3,4a,8a,9,11a-octahydro-5H-4,6,8-trioxa-pentaleno[6a,1-a]naphthalene-2-carboxylic acid (201025-04-9)

Guidance literature:

(2R,4aR,6S,6aS,7S,9R,9aS,9bS)-6-Methoxy-2-phenyl-9a-propionyl-octahydro-cyclopenta[4,5]pyrano[3,2-d][1,3]dioxine-7,9-dicarbaldehyde; With methanol; potassium hydroxide;

With jones reagent;

DOI:10.1021/ol061390i

upstream raw materials:

(1S,2S,3S,5R,8R,10S,11S,12R)-10-methoxy-5-phenyl-2-(1-oxopropyl)-4,6,9-trioxatetracyclo[10.2.1.0^2,11.0^3,8]pentadec-13-ene

Downstream raw materials:

(2R,2aS,3S,4aR,7R,8aS,8bS,11aR)-3-Methoxy-10-methyl-9-oxo-7-phenyl-1,2,2a,3,4a,8a,9,11a-octahydro-5H-4,6,8-trioxa-pentaleno[6a,1-a]naphthalene-2-carboxylic acid