ethyl 2-(5-(3-chloro-2-fluorobenzyl)-2,4-dimethoxybenzoyl)-3-((S)-1-hydroxymethyl-2-methylpropylamino)acrylate

Base Information

Chemical Name:ethyl 2-(5-(3-chloro-2-fluorobenzyl)-2,4-dimethoxybenzoyl)-3-((S)-1-hydroxymethyl-2-methylpropylamino)acrylate
CAS No.:949465-83-2
Molecular Formula:C₂₆H₃₁ClFNO₆
Molecular Weight:507.987
Hs Code.:

Synonyms:ethyl 2-(5-(3-chloro-2-fluorobenzyl)-2,4-dimethoxybenzoyl)-3-((S)-1-hydroxymethyl-2-methylpropylamino)acrylate

Suppliers and Price of ethyl 2-(5-(3-chloro-2-fluorobenzyl)-2,4-dimethoxybenzoyl)-3-((S)-1-hydroxymethyl-2-methylpropylamino)acrylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of ethyl 2-(5-(3-chloro-2-fluorobenzyl)-2,4-dimethoxybenzoyl)-3-((S)-1-hydroxymethyl-2-methylpropylamino)acrylate

Chemical Property:

Purity/Quality:: 95%-98% ^*data from raw suppliers

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Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of ethyl 2-(5-(3-chloro-2-fluorobenzyl)-2,4-dimethoxybenzoyl)-3-((S)-1-hydroxymethyl-2-methylpropylamino)acrylate

There total 1 articles about ethyl 2-(5-(3-chloro-2-fluorobenzyl)-2,4-dimethoxybenzoyl)-3-((S)-1-hydroxymethyl-2-methylpropylamino)acrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2026-48-4,473-75-6
(S)-valinol

: 949465-82-1
ethyl 2-(5-(3-chloro-2-fluorobenzyl)-2,4-dimethoxybenzoyl)-3-dimethylaminoacrylate

: 949465-83-2
ethyl 2-(5-(3-chloro-2-fluorobenzyl)-2,4-dimethoxybenzoyl)-3-((S)-1-hydroxymethyl-2-methylpropylamino)acrylate

Guidance literature:: In toluene; at 18 - 25 ℃; for 1h;

Reference yield: 79.7%

: 949465-83-2
ethyl 2-(5-(3-chloro-2-fluorobenzyl)-2,4-dimethoxybenzoyl)-3-((S)-1-hydroxymethyl-2-methylpropylamino)acrylate

: 18162-48-6
tert-butyldimethylsilyl chloride

: 949465-84-3
ethyl 2-(5-(3-chloro-2-fluorobenzyl)-2,4-dimethoxybenzoyl)-3-((S)-1-(tert-butyldimethylsilanyloxymethyl)-2-methylpropylamino)acrylate

Guidance literature:: With 1H-imidazole; In tetrahydrofuran; toluene; at 50 - 70 ℃; for 3h;

Reference yield:

: 949465-83-2
ethyl 2-(5-(3-chloro-2-fluorobenzyl)-2,4-dimethoxybenzoyl)-3-((S)-1-hydroxymethyl-2-methylpropylamino)acrylate

: (S)-ethyl 6-(3-chloro-2-fluorobenzyl)-1,4-dihydro-1-(1-hydroxy-3-methylbutan-2-yl)-7-methoxy-4-oxoquinoline-3-carboxylate

Guidance literature:: ethyl 2-(5-(3-chloro-2-fluorobenzyl)-2,4-dimethoxybenzoyl)-3-((S)-1-hydroxymethyl-2-methylpropylamino)acrylate; With N,O-bis-(trimethylsilyl)-acetamide; potassium chloride; In N,N-dimethyl-formamide; at 90 - 100 ℃; for 1h;

With hydrogenchloride; In water; N,N-dimethyl-formamide; at 20 - 35 ℃; for 0.166667 - 0.333333h;