[4-(bis-pyridin-2-ylmethyl-amino)-phenyl]-(4,5-dimethoxy-2-nitro-phenyl)-methanol

Base Information

• Chemical Name: [4-(bis-pyridin-2-ylmethyl-amino)-phenyl]-(4,5-dimethoxy-2-nitro-phenyl)-methanol
• CAS No.: 1203669-58-2
• Molecular Formula: C₂₇H₂₆N₄O₅
• Molecular Weight: 486.527
• Mol file: 1203669-58-2.mol

Synonyms:[4-(bis-pyridin-2-ylmethyl-amino)-phenyl]-(4,5-dimethoxy-2-nitro-phenyl)-methanol

Chemical Property of [4-(bis-pyridin-2-ylmethyl-amino)-phenyl]-(4,5-dimethoxy-2-nitro-phenyl)-methanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [4-(bis-pyridin-2-ylmethyl-amino)-phenyl]-(4,5-dimethoxy-2-nitro-phenyl)-methanol

There total 2 articles about [4-(bis-pyridin-2-ylmethyl-amino)-phenyl]-(4,5-dimethoxy-2-nitro-phenyl)-methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.3%

bis-pyridin-2-ylmethyl-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-phenyl]-amine (1203669-57-1) + 6-nitroveratraldehyde (20357-25-9) → [4-(bis-pyridin-2-ylmethyl-amino)-phenyl]-(4,5-dimethoxy-2-nitro-phenyl)-methanol (1203669-58-2)

Guidance literature:

With tri-1-napthylphosphine; potassium carbonate; palladium dichloride; In tetrahydrofuran; at 60 ℃; for 60h;

DOI:10.1039/b913605c

Reference yield: 33.5%

[4-(bis-pyridin-2-ylmethyl-amino)-phenyl]-(4,5-dimethoxy-2-nitro-phenyl)-methanone (1203669-56-0) → [4-(bis-pyridin-2-ylmethyl-amino)-phenyl]-(4,5-dimethoxy-2-nitro-phenyl)-methanol (1203669-58-2)

Guidance literature:

With sodium tetrahydroborate; In acetonitrile; at 0 - 70 ℃;

DOI:10.1039/b913605c

Reference yield: 69.0%

[4-(bis-pyridin-2-ylmethyl-amino)-phenyl]-(4,5-dimethoxy-2-nitro-phenyl)-methanol (1203669-58-2) → [4-(bis-pyridin-2-ylmethyl-amino)-phenyl]-(4,5-dimethoxy-2-nitroso-phenyl)-methanone (1203669-54-8)

Guidance literature:

In acetonitrile; at 25 ℃; for 4h; Photolysis;

DOI:10.1039/b913605c

upstream raw materials:

bis-pyridin-2-ylmethyl-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-phenyl]-amine

6-nitroveratraldehyde

[4-(bis-pyridin-2-ylmethyl-amino)-phenyl]-(4,5-dimethoxy-2-nitro-phenyl)-methanone

Downstream raw materials:

[4-(bis-pyridin-2-ylmethyl-amino)-phenyl]-(4,5-dimethoxy-2-nitroso-phenyl)-methanone

[4-(bis-pyridin-2-ylmethyl-amino)-phenyl]-(4,5-dimethoxy-2-nitro-phenyl)-methanone