<2-<3,6-Bis(dimethylamino)-10-acridinio>ethyl> (2,3-Di-O-palmitoyl-D,L-1-glyceryl) Phosphate

Base Information

Chemical Name:<2-<3,6-Bis(dimethylamino)-10-acridinio>ethyl> (2,3-Di-O-palmitoyl-D,L-1-glyceryl) Phosphate
CAS No.:80212-83-5
Molecular Formula:C₅₄H₉₀N₃O₈P
Molecular Weight:940.298
Hs Code.:

Synonyms:<2-<3,6-Bis(dimethylamino)-10-acridinio>ethyl> (2,3-Di-O-palmitoyl-D,L-1-glyceryl) Phosphate

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Chemical Property of <2-<3,6-Bis(dimethylamino)-10-acridinio>ethyl> (2,3-Di-O-palmitoyl-D,L-1-glyceryl) Phosphate

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Technology Process of <2-<3,6-Bis(dimethylamino)-10-acridinio>ethyl> (2,3-Di-O-palmitoyl-D,L-1-glyceryl) Phosphate

There total 4 articles about <2-<3,6-Bis(dimethylamino)-10-acridinio>ethyl> (2,3-Di-O-palmitoyl-D,L-1-glyceryl) Phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 494-38-2
acridine orange

: 80212-83-5,91097-44-8
<2-<3,6-Bis(dimethylamino)-10-acridinio>ethyl> (2,3-Di-O-palmitoyl-D,L-1-glyceryl) Phosphate

Guidance literature:: Multi-step reaction with 4 steps

1: 2) AgCl / 1) benzene, 16 h, reflux, 2) MeOH, water, 15 h

2: 1) tosyl chloride, 2) NaHCO₃, aq. KI / 1) DMF, pyridine, 120 - 130 deg C, 60 min, 2) water

3: 1) NaI / 1) ethyleneglycol, 120 deg C, 5 h, 2) CH₃OH

4: 2) H₂ / 2) 5percent Pd/Al₂O₃ / 1) CH₃CN, C₆H₆, 110 - 120 deg C, 25 h, 2) C₂H₅OH, 6 h

With hydrogen; sodium hydrogencarbonate; p-toluenesulfonyl chloride; potassium iodide; sodium iodide; silver(I) chloride; palladium/alumina;

Reference yield:

: 80212-80-2
10-(2-Chlorethyl)-3,6-bis(dimethylamino)acridinium-iodid

: 80212-83-5,91097-44-8
<2-<3,6-Bis(dimethylamino)-10-acridinio>ethyl> (2,3-Di-O-palmitoyl-D,L-1-glyceryl) Phosphate

Guidance literature:: Multi-step reaction with 2 steps

1: 1) NaI / 1) ethyleneglycol, 120 deg C, 5 h, 2) CH₃OH

2: 2) H₂ / 2) 5percent Pd/Al₂O₃ / 1) CH₃CN, C₆H₆, 110 - 120 deg C, 25 h, 2) C₂H₅OH, 6 h

With hydrogen; sodium iodide; palladium/alumina;

Reference yield:

: 80212-79-9
3,6-Bis(dimethylamino)-10-(2-hydroxyethyl)acridinium-chlorid

: 80212-83-5,91097-44-8
<2-<3,6-Bis(dimethylamino)-10-acridinio>ethyl> (2,3-Di-O-palmitoyl-D,L-1-glyceryl) Phosphate

Guidance literature:: Multi-step reaction with 3 steps

1: 1) tosyl chloride, 2) NaHCO₃, aq. KI / 1) DMF, pyridine, 120 - 130 deg C, 60 min, 2) water

2: 1) NaI / 1) ethyleneglycol, 120 deg C, 5 h, 2) CH₃OH

3: 2) H₂ / 2) 5percent Pd/Al₂O₃ / 1) CH₃CN, C₆H₆, 110 - 120 deg C, 25 h, 2) C₂H₅OH, 6 h

With hydrogen; sodium hydrogencarbonate; p-toluenesulfonyl chloride; potassium iodide; sodium iodide; palladium/alumina;