80212-79-9Relevant academic research and scientific papers
Synthesis and Properties of the Lecithin Analogous Fluorochrome. ethyl> 2,3-Di-O-palmitoyl-D,L-1-glyceryl Phosphate
Erbrich, Uwe,Zimmermann, Herbert W.
, p. 3372 - 3377 (2007/10/02)
The reaction of 3,6-bis(dimethylamino)acridine (1) with 2-bromoethanol yields 3,6-bis(dimethylamino)-10-(2-hydroxyethyl)acridinium bromide.Successive treatment of the corresponding chloride 2 with tosyl chloride, sodium iodide, and picric acid results in the formation of 3,6-bis(dimethylamino)-10-(2-iodoethyl)acridinium picrate (4).By means of silver benzyl 2,3-di-O-palmitoyl-D,L-glycerol 1-phosphate (5), 4 is transformed into the lecithin derivative (6).The structure was determined by 1H-NMR spectroscopy.The results of some staining tests with LM-and Hela cells are reported.
