Tiazuril

Base Information

Chemical Name:Tiazuril
CAS No.:35319-70-1
Molecular Formula:C17H14 Cl N3 O2 S
Molecular Weight:359.83
Hs Code.:2933699090
UNII:14LS8QHX0U
DSSTox Substance ID:DTXSID30188825
Nikkaji Number:J19.682G
Wikidata:Q27251636
NCI Thesaurus Code:C76433
Metabolomics Workbench ID:45139
ChEMBL ID:CHEMBL27999
Mol file:35319-70-1.mol

Synonyms:tiazuril

Suppliers and Price of Tiazuril

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
TIAZURIL 95.00%
5MG
$ 502.22

Total 4 raw suppliers

Chemical Property of Tiazuril

Chemical Property:

Boiling Point:°Cat760mmHg
PKA:6.45±0.20(Predicted)
Flash Point:°C
PSA：93.05000
Density:1.39g/cm³
LogP:3.34220
XLogP3:4.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:359.0495256
Heavy Atom Count:24
Complexity:510

Purity/Quality:

99% ^*data from raw suppliers

TIAZURIL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC(=CC(=C1SC2=CC=C(C=C2)Cl)C)N3C(=O)NC(=O)C=N3

Technology Process of Tiazuril

There total 4 articles about Tiazuril which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 40913-49-3
2-[4-(4-chloro-phenylsulfanyl)-3,5-dimethyl-phenyl]-3,5-dioxo-2,3,4,5-tetrahydro-[1,2,4]triazine-6-carboxylic acid

: 35319-70-1
2-<3,5-dimethyl-4-<(p-chlorophenyl)thio>phenyl>-as-triazine-3,5(2H,4H)-dione

Guidance literature:: With mercaptoacetic acid; at 140 ℃; for 3h;
DOI:10.1021/jm00143a015

Reference yield:

: 38560-98-4
4-Amino-4'-chlor-2,6-dimethyldiphenylsulfid

: 35319-70-1
2-<3,5-dimethyl-4-<(p-chlorophenyl)thio>phenyl>-as-triazine-3,5(2H,4H)-dione

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) sodium nitrite, glacial acetic acid, concd. HCl, 2.) aq. acetic acid / 1.) 10 deg C, 15 min, 2.) RT, 1 h

2: sodium acetate, aq. H₂SO₄ / 6 h / Heating

3: aq. HCl / 1 h / Ambient temperature; pH 2.0

4: thioglycolic acid / 3 h / 140 °C

With hydrogenchloride; sulfuric acid; sodium acetate; acetic acid; mercaptoacetic acid; sodium nitrite;
DOI:10.1021/jm00143a015

Reference yield:

: 53334-37-5
(2-{[4-(4-Chloro-phenylsulfanyl)-3,5-dimethyl-phenyl]-hydrazono}-3-ethoxycarbonylamino-3-oxo-propionyl)-carbamic acid ethyl ester

: 35319-70-1
2-<3,5-dimethyl-4-<(p-chlorophenyl)thio>phenyl>-as-triazine-3,5(2H,4H)-dione

Guidance literature:: Multi-step reaction with 3 steps

1: sodium acetate, aq. H₂SO₄ / 6 h / Heating

2: aq. HCl / 1 h / Ambient temperature; pH 2.0

3: thioglycolic acid / 3 h / 140 °C

With hydrogenchloride; sulfuric acid; sodium acetate; mercaptoacetic acid;
DOI:10.1021/jm00143a015