(R)-((R)-1-Oxo-indan-2-yl)-((R)-1-phenyl-ethylamino)-acetic acid

Base Information

• Chemical Name: (R)-((R)-1-Oxo-indan-2-yl)-((R)-1-phenyl-ethylamino)-acetic acid
• CAS No.: 847153-94-0
• Molecular Formula: C₁₉H₁₉NO₃
• Molecular Weight: 309.365
• Mol file: 847153-94-0.mol

Synonyms:(R)-((R)-1-Oxo-indan-2-yl)-((R)-1-phenyl-ethylamino)-acetic acid

Chemical Property of (R)-((R)-1-Oxo-indan-2-yl)-((R)-1-phenyl-ethylamino)-acetic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of (R)-((R)-1-Oxo-indan-2-yl)-((R)-1-phenyl-ethylamino)-acetic acid

There total 1 articles about (R)-((R)-1-Oxo-indan-2-yl)-((R)-1-phenyl-ethylamino)-acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

(R)-1-phenyl-ethyl-amine (3886-69-9) + 1-oxoindan-Δ2,α-acetic acid (114915-75-2) → (R)-((R)-1-Oxo-indan-2-yl)-((R)-1-phenyl-ethylamino)-acetic acid (847153-94-0)

Guidance literature:

In methanol; water; at 20 ℃; for 120h;

DOI:10.1016/j.tetlet.2004.12.048

Reference yield: 64.0%

(R)-((R)-1-Oxo-indan-2-yl)-((R)-1-phenyl-ethylamino)-acetic acid (847153-94-0) → (R)-((1R,2R)-1-Hydroxy-indan-2-yl)-((R)-1-phenyl-ethylamino)-acetic acid

Guidance literature:

With sodium tetrahydroborate; In methanol;

DOI:10.1016/j.tetlet.2004.12.048

Reference yield: 63.0%

(R)-((R)-1-Oxo-indan-2-yl)-((R)-1-phenyl-ethylamino)-acetic acid (847153-94-0) → (2R)-amino(2,3-dihydro-1H-inden-2-yl)ethanoic acid (181227-46-3,155239-51-3,16655-71-3)

Guidance literature:

With hydrogen; palladium on activated charcoal; In hydrogenchloride; methanol;

DOI:10.1016/j.tetlet.2004.12.048

upstream raw materials:

(R)-1-phenyl-ethyl-amine

1-oxoindan-Δ^2,α-acetic acid

Downstream raw materials:

(2R)-amino(2,3-dihydro-1H-inden-2-yl)ethanoic acid